Clinical significance of TP53, BIRC3, ATM and MAPK-ERK genes in chronic lymphocytic leukaemia: data from the randomised UK LRF CLL4 trial.

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作者： Stuart J,Blakemore ^[1] ; Ruth,Clifford ^[2] ; Helen,Parker ^[3] ; Pavlos,Antoniou ^[1] ; Ewa,Stec-Dziedzic ^[3] ; Marta,Larrayoz ^[3] ; Zadie,Davis ^[1] ; Latha,Kadalyayil ^[4] ; Andrew,Colins ^[5] ; Pauline,Robbe ^[5] ; Dimitris,Vavoulis ^[3] ; Jade,Forster ^[3] ; Louise,Carr ^[1] ; Ricardo,Morilla ^[1] ; Monica,Else ^[6] ; Dean,Bryant ^[6] ; Helen,McCarthy ^[1] ; Renata J,Walewska ^[4] ; Andrew J,Steele ^[4] ; Jacqueline,Chan ^[1] ; Graham,Speight ^[7] ; Tanja,Stankovic ^[7] ; Mark S,Cragg ^[8] ; Daniel,Catovsky ^[1] ; David G,Oscier ^[9] ; Matthew J J,Rose-Zerilli ^[6] ; Anna,Schuh ^[4] ; Jonathan C,Strefford ^[1]

作者单位： Academic Unit of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK. ^[1] Department I of Internal Medicine, Centre of Excellence in Aging Research, University of Cologne, Cologne, Germany. ^[2] Oxford National Institute for Health Research Biomedical Research Centre and Department of Oncology, University of Oxford, Oxford, UK. ^[3] Department of Molecular Pathology, Royal Bournemouth Hospital, Bournemouth, UK. ^[4] Genetic Epidemiology and Bioinformatics, Faculty of Medicine, University of Southampton, Southampton, UK. ^[5] Division of Molecular Pathology, The Institute of Cancer Research, London, UK. ^[6] Oxford Gene Technology, Begbroke Science Park, Begbroke, Oxfordshire, UK. ^[7] Institute of Cancer and Genomic Sciences, College of Medical and Dental Services, IBR West, University of Birmingham, Birmingham, UK. ^[8] Antibody & Vaccine Group, Centre for Cancer Immunology, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK. ^[9] Academic Unit of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK. jcs@soton.ac.uk. ^[10]