Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression.

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第一作者： Niklas,Mejhert

第一单位： Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

作者： Niklas,Mejhert ^[1] ; Leena,Kuruvilla ^[2] ; Katlyn R,Gabriel ^[3] ; Shane D,Elliott ^[3] ; Marie-Aude,Guie ^[2] ; Huajin,Wang ^[2] ; Zon Weng,Lai ^[1] ; Elizabeth A,Lane ^[4] ; Romain,Christiano ^[1] ; Nika N,Danial ^[4] ; Robert V,Farese ^[5] ; Tobias C,Walther ^[6]

作者单位： Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. ^[1] Department of Cell Biology, Yale School of Medicine, New Haven, CT 06510, USA. ^[2] Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Boston, MA 02115, USA. ^[3] Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. ^[4] Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address: robert@hsph.harvard.edu. ^[5] Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address: twalther@hsph.harvard.edu. ^[6]

关键词 ChREBP MLX MLXIP MLXIPL MondoA MondoB glucose lipid droplets metabolism transcription factor