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首页> International journal of molecular sciences> Discovery of a Gatekeeper Residue in the C-Terminal Tail of the Extracellular Signal-Regulated Protein Kinase 5 (ERK5).

Discovery of a Gatekeeper Residue in the C-Terminal Tail of the Extracellular Signal-Regulated Protein Kinase 5 (ERK5).

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作者： Adam J,Pearson ^[1] ; Paul,Fullwood ^[2] ; Gabriela,Toro Tapia ^[2] ; Ian,Prise ^[3] ; Michael P,Smith ^[2] ; Qiuping,Xu ^[1] ; Allan,Jordan ^[4] ; Emanuele,Giurisato ^[1] ; Alan J,Whitmarsh ^[5] ; Chiara,Francavilla ^[2] ; Cathy,Tournier ^[2]

作者单位： Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK. ^[1] Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK. ^[2] Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK. ^[3] Drug Discovery Unit, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M13 9PT, UK. ^[4] Department of Biotechnology Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy. ^[5]

关键词 ERK5 MAPK mass spectrometry phosphorylation proteomics transcription

主题词结合部位(Binding Sites);细胞核(Cell Nucleus);人类(Humans);质谱分析法(Mass Spectrometry);丝裂原活化蛋白激酶7(Mitogen-Activated Protein Kinase 7);磷酰化(Phosphorylation);蛋白质结合(Protein Binding);蛋白质加工, 转译后(Protein Processing, Post-Translational);蛋白质转运(Protein Transport);蛋白质组学(Proteomics);信号传导(Signal Transduction);苏氨酸(Threonine);转录, 遗传(Transcription, Genetic)

DOI 10.3390/ijms21030929

PMID 32023819

发布时间 2024-02-10

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International journal of molecular sciences

International journal of molecular sciences

2020年21卷3期

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