作者：
Giada,Mondanelli [1]
;
Alice,Coletti [2]
;
Francesco Antonio,Greco [2]
;
Maria Teresa,Pallotta [1]
;
Ciriana,Orabona [1]
;
Alberta,Iacono [1]
;
Maria Laura,Belladonna [1]
;
Elisa,Albini [1]
;
Eleonora,Panfili [2]
;
Francesca,Fallarino [1]
;
Marco,Gargaro [1]
;
Giorgia,Manni [1]
;
Davide,Matino [1]
;
Agostinho,Carvalho [1]
;
Cristina,Cunha [3]
;
Patricia,Maciel [4]
;
Massimiliano,Di Filippo [3]
;
Lorenzo,Gaetani [4]
;
Roberta,Bianchi [3]
;
Carmine,Vacca [4]
;
Ioana Maria,Iamandii [5]
;
Elisa,Proietti [5]
;
Francesca,Boscia [1]
;
Lucio,Annunziato [1]
;
Maikel,Peppelenbosch [1]
;
Paolo,Puccetti [1]
;
Paolo,Calabresi [6]
;
Antonio,Macchiarulo [6]
;
Laura,Santambrogio [7]
;
Claudia,Volpi [1]
;
Ursula,Grohmann [5]
作者单位：
Department of Experimental Medicine, University of Perugia, 06100 Perugia, Italy.
[1]
Department of Pharmaceutical Sciences, University of Perugia, 06100 Perugia, Italy.
[2]
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
[3]
ICVS/3B's-PT Government Associate Laboratory, 4704-553 Braga/Guimarães, Portugal.
[4]
Department of Medicine, University of Perugia, 06100 Perugia, Italy.
[5]
Department of Neuroscience, University of Naples Federico II, 80131 Naples, Italy.
[6]
Department of Gastroenterology and Hepatology, Erasmus Medical Centre-University Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
[7]
Englander Institute of Precision Medicine, Weill Cornell Medicine, New York, NY 10065.
[8]
Department of Radiation Oncology, Weill Cornell Medicine, New York, NY 10065.
[9]
Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065.
[10]
Department of Experimental Medicine, University of Perugia, 06100 Perugia, Italy; claudia.volpi@unipg.it ursula.grohmann@unipg.it.
[11]
Department of Pathology, Albert Einstein College of Medicine, New York, NY 10461.
[12]
主题词
别构调节(Allosteric Regulation);别构部位(Allosteric Site);动物(Animals);生物催化(Biocatalysis);疾病模型, 动物(Disease Models, Animal);脑脊髓炎, 自身免疫性, 实验性(Encephalomyelitis, Autoimmune, Experimental);女(雌)性(Female);人类(Humans);吲哚胺-吡咯2,3-双加氧酶(Indoleamine-Pyrrole 2,3,-Dioxygenase);犬尿氨酸(Kynurenine);白细胞, 单核(Leukocytes, Mononuclear);男(雄)性(Male);小鼠, 基因敲除(Mice, Knockout);多发性硬化(Multiple Sclerosis);血清素(Serotonin);色氨酸(Tryptophan)
DOI
10.1073/pnas.1918215117
PMID
32024760
发布时间
2021-11-08
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