GPR30-Expressing Gastric Chief Cells Do Not Dedifferentiate But Are Eliminated via PDK-Dependent Cell Competition During Development of Metaplasia.-论文-万方医学网

第一作者： Masahiro,Hata

第一单位： Department of Gastroenterology, Graduate school of Medicine, the University of Tokyo, Tokyo, Japan.

作者： Masahiro,Hata ^[1] ; Hiroto,Kinoshita ^[2] ; Yoku,Hayakawa ^[3] ; Mitsuru,Konishi ^[1] ; Mayo,Tsuboi ^[1] ; Yukiko,Oya ^[1] ; Ken,Kurokawa ^[1] ; Yuki,Hayata ^[1] ; Hayato,Nakagawa ^[1] ; Keisuke,Tateishi ^[1] ; Hiroaki,Fujiwara ^[4] ; Yoshihiro,Hirata ^[5] ; Daniel L,Worthley ^[6] ; Yuki,Muranishi ^[7] ; Takahisa,Furukawa ^[7] ; Shunsuke,Kon ^[8] ; Hiroyuki,Tomita ^[9] ; Timothy C,Wang ^[10] ; Kazuhiko,Koike ^[1]

作者单位： Department of Gastroenterology, Graduate school of Medicine, the University of Tokyo, Tokyo, Japan. ^[1] Department of Gastroenterology, Graduate school of Medicine, the University of Tokyo, Tokyo, Japan; Department of Gastroenterology, The Institute for Adult Diseases, Asahi-life Foundation, Tokyo, Japan. ^[2] Department of Gastroenterology, Graduate school of Medicine, the University of Tokyo, Tokyo, Japan. Electronic address: yhayakawa-tky@umin.ac.jp. ^[3] Department of Gastroenterology, The Institute for Adult Diseases, Asahi-life Foundation, Tokyo, Japan. ^[4] Division of Advanced Genome Medicine, The Institute of Medical Science, the University of Tokyo, Tokyo, Japan. ^[5] Cancer Theme, South Australian Health and Medical Research Institute, South Australia, Australia. ^[6] Laboratory for Molecular and Developmental Biology, Institute for Protein Research, Osaka University, Osaka, Japan. ^[7] Tokyo University of Science, Division of Development and Aging, Research Institute for Biomedical Sciences, Chiba, Japan. ^[8] Department of Tumor Pathology, Gifu University Graduate School of Medicine, Gifu, Japan. ^[9] Division of Digestive and Liver Disease, Department of Medicine, Columbia University, New York, New York. ^[10]

主题词动物(Animals);吖丁啶类(Azetidines);细胞间通讯(Cell Communication);细胞分化(Cell Differentiation);细胞谱系(Cell Lineage);主细胞, 胃(Chief Cells, Gastric);疾病模型, 动物(Disease Models, Animal);胃黏膜(Gastric Mucosa);螺杆菌感染(Helicobacter Infections);幽门螺杆菌(Helicobacter pylori);人类(Humans);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);化生(Metaplasia);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);哌嗪类(Piperazines);受体, 雌激素(Receptors, Estrogen);受体, G-蛋白偶联(Receptors, G-Protein-Coupled);干细胞(Stem Cells);他莫昔芬(Tamoxifen)

DOI 10.1053/j.gastro.2020.01.046

PMID 32032583

发布时间 2023-06-03

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GPR30-Expressing Gastric Chief Cells Do Not Dedifferentiate But Are Eliminated via PDK-Dependent Cell Competition During Development of Metaplasia.

Gastroenterology

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Gastroenterology

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GPR30-Expressing Gastric Chief Cells Do Not Dedifferentiate But Are Eliminated via PDK-Dependent Cell Competition During Development of Metaplasia.

Gastroenterology

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Gastroenterology

相关期刊

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