Chronic mTOR activation induces a degradative smooth muscle cell phenotype.

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作者： Guangxin,Li ^[1] ; Mo,Wang ^[2] ; Alexander W,Caulk ^[1] ; Nicholas A,Cilfone ^[3] ; Sharvari,Gujja ^[4] ; Lingfeng,Qin ^[4] ; Pei-Yu,Chen ^[1] ; Zehua,Chen ^[5] ; Sameh,Yousef ^[4] ; Yang,Jiao ^[1] ; Changshun,He ^[1] ; Bo,Jiang ^[1] ; Arina,Korneva ^[1] ; Matthew R,Bersi ^[3] ; Guilin,Wang ^[3] ; Xinran,Liu ^[6] ; Sameet,Mehta ^[7] ; Arnar,Geirsson ^[8] ; Jeffrey R,Gulcher ^[9] ; Thomas W,Chittenden ^[1] ; Michael,Simons ^[10] ; Jay D,Humphrey ^[4] ; George,Tellides ^[4]

作者单位： Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA. ^[1] Department of Breast and Thyroid Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, China. ^[2] Department of Biomedical Engineering, Yale School of Engineering and Applied Science, New Haven, Connecticut, USA. ^[3] Computational Statistics and Bioinformatics Group, Advanced Artificial Intelligence Research Laboratory, WuXi NextCODE, Cambridge, Massachusetts, USA. ^[4] Internal Medicine. ^[5] Molecular Biophysics and Biochemistry, and. ^[6] Cell Biology, Yale School of Medicine, New Haven, Connecticut, USA. ^[7] Center for Cellular and Molecular Imaging, EM Core Facility, Yale School of Medicine, New Haven, Connecticut, USA. ^[8] Genetics and. ^[9] Program in Vascular Biology and Therapeutics, Yale School of Medicine, New Haven, Connecticut, USA. ^[10] Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut, USA. ^[11]

关键词 Cardiovascular disease Vascular Biology