<i>Ficus deltoidea</i> extract down-regulates protein tyrosine phosphatase 1B expression in a rat model of type 2 diabetes mellitus: a new insight into its antidiabetic mechanism.
作者:
关键词
CAT, catalaseDihydroxyolean-12-en-23-oic acidFBG, fasting blood glucoseFD, Ficus deltoidea var. deltoidea JackFicus deltoideaG6Pase, glucose 6-phosphataseGPx, glutathione peroxidaseGSH, reduced glutathioneGlucose 6-phosphataseGlucose transporter-2MDA, malondialdehydeMET, metforminNA, nicotinamidePEPCK, phosphoenolpyruvate carboxykinasePTP, protein tyrosine phosphatasePhosphoenolpyruvate carboxykinaseProtein tyrosine phosphatase 1BSOD, superoxide dismutaseSTZ, streptozotocinSlc2a2, GLUT2 geneT2DM, type 2 diabetes mellitus
主题词
动物(Animals);血糖(Blood Glucose);糖尿病, 实验性(Diabetes Mellitus, Experimental);糖尿病, 2型(Diabetes Mellitus, Type 2);减量调节(Down-Regulation);榕属(Ficus);基因表达(Gene Expression);葡糖-6-磷酸酶(Glucose-6-Phosphatase);降血糖药(Hypoglycemic Agents);胰岛素(Insulin);胰岛素抗药性(Insulin Resistance);肝(Liver);男(雄)性(Male);氧化性应激(Oxidative Stress);植物提取物(Plant Extracts);蛋白质酪氨酸磷酸酶, 非受体1型(Protein Tyrosine Phosphatase, Non-Receptor Type 1);大鼠(Rats);大鼠, Wistar(Rats, Wistar);链脲菌素(Streptozocin)
DOI
10.1017/jns.2019.40
PMID
32042410
发布时间
2024-07-25
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Journal of nutritional science
2020年9卷
e2页
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