Vitamin D receptor targets hepatocyte nuclear factor 4α and mediates protective effects of vitamin D in nonalcoholic fatty liver disease.
第一作者:
Hong,Zhang
第一单位:
Department of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.
作者:
主题词
动物(Animals);疾病模型, 动物(Disease Models, Animal);葡糖耐量试验(Glucose Tolerance Test);肝细胞核因子4(Hepatocyte Nuclear Factor 4);肝细胞(Hepatocytes);人类(Humans);胰岛素抗药性(Insulin Resistance);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);肥胖症(Obesity);预防和防护用药(Protective Agents);RNA干扰(RNA Interference);RNA, 小分子干扰(RNA, Small Interfering);受体, 骨化三醇(Receptors, Calcitriol);增量调节(Up-Regulation);维生素D(Vitamin D)
DOI
10.1074/jbc.RA119.011487
PMID
32051143
发布时间
2021-03-20
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The Journal of biological chemistry
3891-3905页
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