NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis.-论文-万方医学网

第一作者： Sarah,Luiken

第一单位： Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

作者： Sarah,Luiken ^[1] ; Angelika,Fraas ^[1] ; Matthias,Bieg ^[2] ; Raisatun,Sugiyanto ^[1] ; Benjamin,Goeppert ^[1] ; Stephan,Singer ^[1] ; Carolin,Ploeger ^[1] ; Gregor,Warsow ^[3] ; Jens U,Marquardt ^[4] ; Carsten,Sticht ^[5] ; Carolina,De La Torre ^[5] ; Stefan,Pusch ^[6] ; Arianeb,Mehrabi ^[7] ; Norbert,Gretz ^[5] ; Matthias,Schlesner ^[3] ; Roland,Eils ^[8] ; Peter,Schirmacher ^[1] ; Thomas,Longerich ^[1] ; Stephanie,Roessler ^[9]

作者单位： Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany. ^[1] Center for Digital Health, Berlin Institute of Health and Charité - Universitätsmedizin Berlin, Berlin, Germany.;Heidelberg Center for Personalized Oncology (DKFZ-HIPO), Heidelberg, Germany. ^[2] German Cancer Research Center (DKFZ), Bioinformatics and Omics Data Analytics, Heidelberg, Germany. ^[3] First Department of Medicine, University Medical Centre of the Johannes Gutenberg University Mainz, Mainz, Germany. ^[4] Medical Research Centre, University of Heidelberg, Mannheim, Germany. ^[5] Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.;Clinical Cooperation Unit Neuropathology, German Cancer Research Center, Heidelberg, Germany. ^[6] Department of General Visceral and Transplantation Surgery, University Hospital Heidelberg, Heidelberg, Germany. ^[7] Center for Digital Health, Berlin Institute of Health and Charité - Universitätsmedizin Berlin, Berlin, Germany.;Heidelberg Center for Personalized Oncology (DKFZ-HIPO), Heidelberg, Germany.;Health Data Science Unit, University Hospital Heidelberg, Heidelberg, Germany.;Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany. ^[8] Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany. Stephanie.Roessler@med.uni-heidelberg.de. ^[9]

医学主题词动物(Animals);碱性螺旋-环-螺旋转录因子类(Basic Helix-Loop-Helix Transcription Factors);癌, 肝细胞(Carcinoma, Hepatocellular);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);队列研究(Cohort Studies);DNA突变分析(DNA Mutational Analysis);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);肝(Liver);肝肿瘤(Liver Neoplasms);男(雄)性(Male);小鼠(Mice);突变(Mutation);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);受体, Notch(Receptors, Notch);阻遏蛋白质类(Repressor Proteins);信号传导(Signal Transduction);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1038/s41388-020-1198-3

PMID 32055024

发布时间 2022-12-07

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NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis.

Oncogene

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NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis.

Oncogene

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同项目论文

Oncogene

相关期刊

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