首页> Pharmacological research> Berberine-mediated up-regulation of surfactant protein D facilitates cartilage repair by modulating immune responses via the inhibition of TLR4/NF-ĸB signaling.

Berberine-mediated up-regulation of surfactant protein D facilitates cartilage repair by modulating immune responses via the inhibition of TLR4/NF-ĸB signaling.

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第一作者： Yan,Zhou

第一单位： Department of Orthopedics, Renmin Hospital of Wuhan University, 430060 Wuhan, China; Central Laboratory, Renmin Hospital of Wuhan University, 430060, Wuhan, China. Electronic address: yanzhou0827@163.com.

作者： Yan,Zhou ^[1] ; Jianghua,Ming ^[2] ; Ming,Deng ^[3] ; Yaming,Li ^[2] ; Bochun,Li ^[4] ; Jia,Li ^[5] ; Yonggang,Ma ^[2] ; Zhonghui,Chen ^[3] ; Shiqing,Liu ^[2]

作者单位： Department of Orthopedics, Renmin Hospital of Wuhan University, 430060 Wuhan, China; Central Laboratory, Renmin Hospital of Wuhan University, 430060, Wuhan, China. Electronic address: yanzhou0827@163.com. ^[1] Department of Orthopedics, Renmin Hospital of Wuhan University, 430060 Wuhan, China. ^[2] Central Laboratory, Renmin Hospital of Wuhan University, 430060, Wuhan, China. ^[3] Department of Rehabilitation, Wuhan Union Hospital, Huazhong University of Science and Technology, 430022, Wuhan, China. ^[4] College of Acupuncture and Bone Injury, Hubei University of Traditional Chinese Medicine, 430061, Wuhan, China. ^[5]

关键词 Berberine chloride Innate immunity NF-κB Osteoarthritis Surfactant protein D Toll-like receptor 4