Upregulation of SMYD3 and SMYD3 VNTR 3/3 polymorphism increase the risk of hepatocellular carcinoma.-论文-万方医学网

作者： Mai Thanh,Binh ^[1] ; Nghiem Xuan,Hoan ^[2] ; Dao Phuong,Giang ^[3] ; Hoang Van,Tong ^[1] ; C-Thomas,Bock ^[2] ; Heiner,Wedemeyer ^[3] ; Nguyen Linh,Toan ^[2] ; Mai Hong,Bang ^[3] ; Peter G,Kremsner ^[1] ; Christian G,Meyer ^[2] ; Le Huu,Song ^[4] ; Thirumalaisamy P,Velavan ^[1]

作者单位： Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany. ^[1] Vietnamese-German Center for Medical Research (VGCARE), Hanoi, Vietnam. ^[2] 108 Military Central Hospital, Hanoi, Vietnam. ^[3] Vietnam Military Medical University, Hanoi, Vietnam. ^[4] Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany. ^[5] Department of Gastroenterology and Hepatology, Essen University Hospital, University of Duisburg-Essen, Essen, Germany. ^[6] Duy Tan University, Da Nang, Vietnam. ^[7] Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany. velavan@medizin.uni-tuebingen.de. ^[8] Vietnamese-German Center for Medical Research (VGCARE), Hanoi, Vietnam. velavan@medizin.uni-tuebingen.de. ^[9] Duy Tan University, Da Nang, Vietnam. velavan@medizin.uni-tuebingen.de. ^[10]

主题词青少年(Adolescent);成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);癌, 肝细胞(Carcinoma, Hepatocellular);病例对照研究(Case-Control Studies);儿童(Child);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);疾病遗传易感性(Genetic Predisposition to Disease);乙型肝炎, 慢性(Hepatitis B, Chronic);组蛋白赖氨酸N-甲基转移酶(Histone-Lysine N-Methyltransferase);人类(Humans);肝硬化(Liver Cirrhosis);肝肿瘤(Liver Neoplasms);男(雄)性(Male);中年人(Middle Aged);小卫星重复(Minisatellite Repeats);多态现象, 遗传(Polymorphism, Genetic);启动区, 遗传(Promoter Regions, Genetic);危险因素(Risk Factors);青年人(Young Adult)

DOI 10.1038/s41598-020-59667-z

PMID 32071406

发布时间 2021-02-17

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Upregulation of SMYD3 and SMYD3 VNTR 3/3 polymorphism increase the risk of hepatocellular carcinoma.

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Upregulation of SMYD3 and SMYD3 VNTR 3/3 polymorphism increase the risk of hepatocellular carcinoma.

Scientific reports

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Scientific reports

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