Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma.

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作者： Zenon,Konteatis ^[1] ; Erin,Artin ^[1] ; Brandon,Nicolay ^[1] ; Kimberly,Straley ^[1] ; Anil K,Padyana ^[1] ; Lei,Jin ^[1] ; Yue,Chen ^[1] ; Rohini,Narayaraswamy ^[1] ; Shuilong,Tong ^[2] ; Feng,Wang ^[3] ; Ding,Zhou ^[4] ; Dawei,Cui ^[4] ; Zhenwei,Cai ^[4] ; Zhiyong,Luo ^[5] ; Cheng,Fang ^[5] ; Huachun,Tang ^[5] ; Xiaobing,Lv ^[5] ; Raj,Nagaraja ^[1] ; Hua,Yang ^[1] ; Shin-San M,Su ^[1] ; Zhihua,Sui ^[1] ; Lenny,Dang ^[1] ; Katharine,Yen ^[1] ; Janeta,Popovici-Muller ^[1] ; Paolo,Codega ^[6] ; Carl,Campos ^[6] ; Ingo K,Mellinghoff ^[6] ; Scott A,Biller ^[1]

作者单位： Agios Pharmaceuticals, Inc., Cambridge, Massachusetts 02139, United States. ^[1] Viva Biotech, Shanghai 201203, China. ^[2] Wuxi Biortus Biosciences Co. Ltd, Jiangyin 214437, China. ^[3] PharmaResources, Shanghai 201201, China. ^[4] ChemPartner, Shanghai 201203, China. ^[5] Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States. ^[6]

DOI 10.1021/acsmedchemlett.9b00509

PMID 32071674

发布时间 2020-10-02

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ACS medicinal chemistry letters

2020年11卷2期

101-107页

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Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma.

ACS medicinal chemistry letters

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ACS medicinal chemistry letters

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Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma.

ACS medicinal chemistry letters

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ACS medicinal chemistry letters

相关期刊

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