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Extracellular HMGB1 exacerbates autoimmune progression and recurrence of type 1 diabetes by impairing regulatory T cell stability.

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作者: Jing,Zhang [1] ; Longmin,Chen [2] ; Faxi,Wang [1] ; Yuan,Zou [2] ; Jingyi,Li [1] ; Jiahui,Luo [2] ; Faheem,Khan [1] ; Fei,Sun [2] ; Yang,Li [1] ; Jing,Liu [1] ; Zhishui,Chen [2] ; Shu,Zhang [1] ; Fei,Xiong [1] ; Qilin,Yu [2] ; Jinxiu,Li [1] ; Kun,Huang [2] ; Bao-Ling,Adam [1] ; Zhiguang,Zhou [2] ; Decio L,Eizirik [1] ; Ping,Yang [3] ; Cong-Yi,Wang [1]
作者单位: The Center for Biomedical Research, Tongji Hospital Research Building, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, Caidian, China. [1] Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Respiratory Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. [2] Key Laboratory of Organ Transplantation, Ministry of Education, NHC Key Laboratory of Organ Transplantation, Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Tongji Hospital, Wuhan, China. [3] Shenzhen Third People's Hospital, Shenzhen, Guangdong, China. [4] Tongji School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. [5] Department of Surgery, Medical College of Georgia at Augusta University, Augusta, GA, USA. [6] Diabetes Center, The Second Xiangya Hospital, Institute of Metabolism and Endocrinology, Central South University, Changsha, China. [7] ULB Center for Diabetes Research, Université Libre de Bruxelles, Brussels, Belgium. [8] The Center for Biomedical Research, Tongji Hospital Research Building, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, Caidian, China. yangping@tjh.tjmu.edu.cn. [9] Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Respiratory Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. yangping@tjh.tjmu.edu.cn. [10] The Center for Biomedical Research, Tongji Hospital Research Building, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, Caidian, China. wangcy@tjh.tjmu.edu.cn. [11] Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Respiratory Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. wangcy@tjh.tjmu.edu.cn. [12] Key Laboratory of Organ Transplantation, Ministry of Education, NHC Key Laboratory of Organ Transplantation, Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Tongji Hospital, Wuhan, China. wangcy@tjh.tjmu.edu.cn. [13]
DOI 10.1007/s00125-020-05105-8
PMID 32072192
发布时间 2021-05-31
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Diabetologia

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