Trans-right ventricle and transpulmonary metabolite gradients in human pulmonary arterial hypertension.

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作者： Philippe,Chouvarine ^[1] ; Martin,Giera ^[2] ; Gabi,Kastenmüller ^[3] ; Anna,Artati ^[4] ; Jerzy,Adamski ^[5] ; Harald,Bertram ^[6] ; Georg,Hansmann ^[1]

作者单位： Department of Pediatric Cardiology and Critical care, Hannover Medical School, Hannover, Germany. ^[1] Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands. ^[2] Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Neuherberg, Germany. ^[3] Research Unit Molecular Endocrinology and Metabolism, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Neuherberg, Germany. ^[4] Research Unit Molecular Endocrinology and Metabolism, Genome Analysis Center, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Neuherberg, Germany. ^[5] Department of Biochemistry, National University Singapore Yong Loo Lin School of Medicine, Singapore. ^[6] Department of Pediatric Cardiology and Critical care, Hannover Medical School, Hannover, Germany georg.hansmann@gmail.com. ^[7]

关键词 PAH biomarker hemodynamics human lipidomics metabolites metabolomics omics trans-RV gradient transpulmonary gradient β-oxidation