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首页> The Journal of physiology> Statin-mediated cholesterol depletion exerts coordinated effects on the alterations in rat vascular smooth muscle cell biomechanics and migration.

Statin-mediated cholesterol depletion exerts coordinated effects on the alterations in rat vascular smooth muscle cell biomechanics and migration.

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作者： Hanna J,Sanyour ^[1] ; Na,Li ^[2] ; Alex P,Rickel ^[1] ; Haydee M,Torres ^[2] ; Ruthellen H,Anderson ^[1] ; Miranda R,Miles ^[2] ; Josh D,Childs ^[3] ; Kevin R,Francis ^[4] ; Jianning,Tao ^[5] ; Zhongkui,Hong ^[6]

作者单位： Department of Biomedical Engineering, University of South Dakota, Sioux Falls, SD, 57107, USA. ^[1] BioSNTR, Sioux Falls, SD, 57107, USA. ^[2] Cancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, SD, 57104, USA. ^[3] Department of Chemistry and Biochemistry, South Dakota State University, Brookings, SD, 57007, USA. ^[4] Cellular Therapies and Stem Cell Biology Group, Sanford Research, Sioux Falls, SD, 57104, USA. ^[5] Department of Pediatrics, Sanford School of Medicine, University of South Dakota, Vermillion, SD, 57069, USA. ^[6] Mechanical Engineering Department, South Dakota State University, Brookings, SD, 57007, USA. ^[7]

关键词 atomic force microscopy cell adhesion cell mechanics cholesterol cytoskeleton fluvastatin vascular smooth muscle cells

主题词动物(Animals);细胞运动(Cell Movement);细胞, 培养的(Cells, Cultured);胆固醇(Cholesterol);人类(Humans);羟甲基戊二酰基CoA还原酶抑制剂(Hydroxymethylglutaryl-CoA Reductase Inhibitors);肌, 平滑, 血管(Muscle, Smooth, Vascular);肌细胞, 平滑肌(Myocytes, Smooth Muscle);大鼠(Rats)

DOI 10.1113/JP279528

PMID 32083311

发布时间 2021-09-17

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The Journal of physiology

The Journal of physiology

2020年598卷8期

1505-1522页

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