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Passenger Mutations in More Than 2,500 Cancer Genomes: Overall Molecular Functional Impact and Consequences.

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第一作者: Sushant,Kumar
第一单位: Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.
作者单位: Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA. [1] Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA; Yale School of Medicine, Yale University, New Haven, CT 06510, USA. [2] Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Yale School of Medicine, Yale University, New Haven, CT 06510, USA. [3] Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Center for Precision Health, School of Biomedical Informatics, University of Texas Health Sciences Center, Houston, TX 77030, USA. [4] Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10021, USA; Department of Physiology and Biophysics, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA. [5] Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany; Faculty of Biosciences, Heidelberg University, Heidelberg 69120, Germany. [6] Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark. [7] Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Department of Biomedical Informatics, College of Medicine, Ohio State University, Columbus, OH 43210, USA; The Ohio State University Comprehensive Cancer Center (OSUCCC-James), Columbus, OH 43210, USA. [8] Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA. [9] Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark; Bioinformatics Research Centre (BiRC), Aarhus University, Aarhus, Denmark. [10] Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany; Health Data Science Unit, Medical Faculty Heidelberg and BioQuant, Heidelberg 69120, Germany. [11] The Broad Institute of MIT and Harvard, Cambridge, MA 02124, USA; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129, USA; Harvard Medical School, 250 Longwood Avenue, Boston, MA 02115, USA. [12] Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10021, USA; Department of Physiology and Biophysics, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA. [13] Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA; Department of Computer Science, Yale University, New Haven, CT 06511, USA. Electronic address: mark@gersteinlab.org. [14]
DOI 10.1016/j.cell.2020.01.032
PMID 32084333
发布时间 2023-11-03
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Cell

Cell

2020年180卷5期

915-927.e16页

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