Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness.-论文-万方医学网

第一作者： Weder Pereira de,Menezes

第一单位： Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, São Paulo 14.784-400, Brazil.

作者： Weder Pereira de,Menezes ^[1] ; Viviane Aline Oliveira,Silva ^[1] ; Izabela Natália Faria,Gomes ^[1] ; Marcela Nunes,Rosa ^[1] ; Maria Luisa Corcoll,Spina ^[1] ; Adriana Cruvinel,Carloni ^[1] ; Ana Laura Vieira,Alves ^[1] ; Matias,Melendez ^[1] ; Gisele Caravina,Almeida ^[2] ; Luciane Sussuchi da,Silva ^[1] ; Carlos,Clara ^[3] ; Isabela Werneck,da Cunha ^[4] ; Glaucia Noeli Maroso,Hajj ^[4] ; Chris,Jones ^[5] ; Lucas Tadeu,Bidinotto ^[6] ; Rui Manuel,Reis ^[7]

作者单位： Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, São Paulo 14.784-400, Brazil. ^[1] Department of Pathology, Barretos Cancer Hospital, Barretos, São Paulo 14.784-400, Brazil. ^[2] Department of Neurosurgery, Barretos Cancer Hospital, Barretos, São Paulo 14.784-400, Brazil. ^[3] A.C Camargo Cancer Center, São Paulo, São Paulo 015.080-10, Brazil. ^[4] Institute of Cancer Research, London, SW7 3RP, UK. ^[5] Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, São Paulo 14.784-400, Brazil.;Barretos School of Health Sciences, Dr. Paulo Prata - FACISB, Barretos, São Paulo 14.785-002, Brazil.;Universidade Estadual Paulista - Unesp, Botucatu Medical School, Department of Pathology, Botucatu, São Paulo 18.618-970, Brazil. ^[6] Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, São Paulo 14.784-400, Brazil.;Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.;B's - PT Government Associate Laboratory, 4806-909 Braga/Guimarães, Portugal. ^[7]

医学主题词青少年(Adolescent);成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);脑肿瘤(Brain Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);儿童(Child);儿童, 学龄前(Child, Preschool);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);神经胶质瘤(Glioma);人类(Humans);婴儿(Infant);男(雄)性(Male);中年人(Middle Aged);肿瘤侵润(Neoplasm Invasiveness);预后(Prognosis);嘌呤核苷磷酸化酶(Purine-Nucleoside Phosphorylase);转染(Transfection);青年人(Young Adult)

DOI 10.3390/cells9020492

PMID 32093414

发布时间 2021-02-19

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Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness.

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Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness.

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