Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance.

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第一作者： Mohamad,Krayem

第一单位： Laboratory of Oncology and Experimental Surgery, Institut Jules Bordet, Université Libre de Bruxelles, 1000 Brussels, Belgium.

作者： Mohamad,Krayem ^[1] ; Philippe,Aftimos ^[2] ; Ahmad,Najem ^[1] ; Tim,van den Hooven ^[3] ; Adriënne,van den Berg ^[3] ; Liesbeth,Hovestad-Bijl ^[3] ; Rik,de Wijn ^[3] ; Riet,Hilhorst ^[3] ; Rob,Ruijtenbeek ^[3] ; Malak,Sabbah ^[1] ; Joseph,Kerger ^[2] ; Ahmad,Awada ^[4] ; Fabrice,Journe ^[1] ; Ghanem E,Ghanem ^[1]

作者单位： Laboratory of Oncology and Experimental Surgery, Institut Jules Bordet, Université Libre de Bruxelles, 1000 Brussels, Belgium. ^[1] Medical Oncology Clinic, Institut Jules Bordet, Université Libre de Bruxelles, 1000 Brussels, Belgium. ^[2] PamGene International BV, 5211HH 's-Hertogenbosch, The Netherlands. ^[3] Laboratory of Oncology and Experimental Surgery, Institut Jules Bordet, Université Libre de Bruxelles, 1000 Brussels, Belgium.;Medical Oncology Clinic, Institut Jules Bordet, Université Libre de Bruxelles, 1000 Brussels, Belgium. ^[4]

关键词 MAPK pathway intrinsic and acquired resistance kinase inhibitors phosphotyrosine kinase serine-threonine kinase

DOI 10.3390/cancers12020512

PMID 32098410

发布时间 2024-07-27

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准确一般字义偏差语意偏离译文作用小提交