Anastrozole has an Association between Degree of Estrogen Suppression and Outcomes in Early Breast Cancer and is a Ligand for Estrogen Receptor α.

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第一作者： James N,Ingle

第一单位： Division of Medical Oncology, Department of Oncology, Mayo Clinic, Rochester, Minnesota. ingle.james@mayo.edu wang.liewei@mayo.edu.

作者： James N,Ingle ^[1] ; Junmei,Cairns ^[2] ; Vera J,Suman ^[3] ; Lois E,Shepherd ^[4] ; Peter A,Fasching ^[5] ; Tanya L,Hoskin ^[3] ; Ravinder J,Singh ^[6] ; Zeruesenay,Desta ^[7] ; Krishna R,Kalari ^[3] ; Matthew J,Ellis ^[8] ; Paul E,Goss ^[9] ; Bingshu E,Chen ^[4] ; Bernhard,Volz ^[10] ; Poulami,Barman ^[3] ; Erin E,Carlson ^[3] ; Tufia,Haddad ^[11] ; Matthew P,Goetz ^[11] ; Barbara,Goodnature ^[12] ; Matthew E,Cuellar ^[13] ; Michael A,Walters ^[13] ; Cristina,Correia ^[2] ; Scott H,Kaufmann ^[2] ; Richard M,Weinshilboum ^[14] ; Liewei,Wang ^[2]

作者单位： Division of Medical Oncology, Department of Oncology, Mayo Clinic, Rochester, Minnesota. ingle.james@mayo.edu wang.liewei@mayo.edu. ^[1] Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota. ^[2] Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota. ^[3] Canadian Cancer Trials Group, Kingston, Ontario, Canada. ^[4] Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital, Erlangen, Germany. ^[5] Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota. ^[6] Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana. ^[7] Department of Medicine, Baylor University College of Medicine, Houston, Texas. ^[8] Massachusetts General Hospital Cancer Center, Harvard University, Boston, Massachusetts. ^[9] Department of Business Informatics, University of Applied Sciences Ansbach, Ansbach, Germany. ^[10] Division of Medical Oncology, Department of Oncology, Mayo Clinic, Rochester, Minnesota. ^[11] Patient advocate, Mayo Clinic Breast Cancer Specialized Program of Research Excellence, Rochester, Minnesota. ^[12] Institute for Therapeutics Discovery and Development, University of Minnesota, Minneapolis, Minnesota. ^[13] Division of Oncology Research, Mayo Clinic, Rochester, Minnesota. ^[14] Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota. ingle.james@mayo.edu wang.liewei@mayo.edu. ^[15]