换一批Combined Targeting of AKT and mTOR Inhibits Proliferation of Human NF1-Associated Malignant Peripheral Nerve Sheath Tumour Cells In Vitro but not in a Xenograft Mouse Model In Vivo.
第一作者：
Alexander,Schulte
第一单位：
Laboratory for Tumor Genetics, Department of Neurology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.
作者：
医学主题词
动物(Animals);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);苯咪唑类(Benzimidazoles);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);药物协同作用(Drug Synergism);杂环化合物, 3环(Heterocyclic Compounds, 3-Ring);人类(Humans);小鼠, SCID(Mice, SCID);吗啉类(Morpholines);神经纤维瘤病1型(Neurofibromatosis 1);神经纤维肉瘤(Neurofibrosarcoma);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.3390/ijms21041548
PMID
32102484
发布时间
2021-12-04
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