Study of chromatographic behavior of antibiotic drugs and their metabolites based on quantitative structure-retention relationships with the use of HPLC-DAD.

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作者： Justyna,Walczak-Skierska ^[1] ; Małgorzata,Szultka-Młyńska ^[2] ; Katarzyna,Pauter ^[3] ; Bogusław,Buszewski ^[1]

作者单位： Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100, Torun, Poland; Centre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University, Wilenska 4, 87-100, Torun, Poland. ^[1] Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100, Torun, Poland. Electronic address: mszultka@umk.pl. ^[2] Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100, Torun, Poland. ^[3]

关键词 Antibiotics HPLC Mechanism retention Quantitative structure–retention relationships

主题词抗菌药(Anti-Bacterial Agents);色谱法, 高压液相(Chromatography, High Pressure Liquid);线性模型(Linear Models);模型, 化学(Models, Chemical);量化构效关系(Quantitative Structure-Activity Relationship);溶剂(Solvents);水(Water)

DOI 10.1016/j.jpba.2020.113187

PMID 32109708

发布时间 2021-01-21

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