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MDM2, MDM4 and EGFR Amplifications and Hyperprogression in Metastatic Acral and Mucosal Melanoma.

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第一作者： Andrea,Forschner

第一单位： Center for Dermatooncology, Department of Dermatology, University Hospital Tübingen, 72076 Tübingen, Germany.

作者： Andrea,Forschner ^[1] ; Franz-Joachim,Hilke ^[2] ; Irina,Bonzheim ^[3] ; Axel,Gschwind ^[2] ; German,Demidov ^[2] ; Teresa,Amaral ^[4] ; Stephan,Ossowski ^[5] ; Olaf,Riess ^[5] ; Christopher,Schroeder ^[2] ; Peter,Martus ^[6] ; Bernhard,Klumpp ^[7] ; Irene,Gonzalez-Menendez ^[3] ; Claus,Garbe ^[1] ; Heike,Niessner ^[1] ; Tobias,Sinnberg ^[1]

作者单位： Center for Dermatooncology, Department of Dermatology, University Hospital Tübingen, 72076 Tübingen, Germany. ^[1] Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen, 72076 Tübingen, Germany. ^[2] Institute of Pathology and Neuropathology, University Hospital Tübingen, 72076 Tübingen, Germany. ^[3] Center for Dermatooncology, Department of Dermatology, University Hospital Tübingen, 72076 Tübingen, Germany.;Portuguese Air Force Health Care Direction, 1649-020 Lisbon, Portugal. ^[4] Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen, 72076 Tübingen, Germany.;German DFG NGS Competence Center, NCCT, 72076 Tübingen, Germany. ^[5] Institute for Clinical Epidemiology and applied Biostatistics (IKEaB), 72076 Tuebingen, Germany. ^[6] Institute for Radiology, Rems-Murr-Kliniken, 71364 Winnenden, Germany. ^[7]

关键词 EGFR MDM2 MDM4 acral melanoma hyperprogression immune checkpoint inhibitors mucosal melanoma

DOI 10.3390/cancers12030540

PMID 32110946

发布时间 2020-09-28

基金项目

2521-0-/TÜFF Habilitation Program for Women of the Faculty of Medicine Tübingen, Germany Forschner_Sinnberg/Hiege Foundation

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