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首页> The Journal of biological chemistry> The microtubule-associated histone methyltransferase SET8, facilitated by transcription factor LSF, methylates α-tubulin.

The microtubule-associated histone methyltransferase SET8, facilitated by transcription factor LSF, methylates α-tubulin.

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作者： Hang Gyeong,Chin ^[1] ; Pierre-Olivier,Esteve ^[2] ; Cristian,Ruse ^[2] ; Jiyoung,Lee ^[3] ; Scott E,Schaus ^[4] ; Sriharsa,Pradhan ^[2] ; Ulla,Hansen ^[5]

作者单位： New England Biolabs, Ipswich, Massachusetts 01938.;MCBB Graduate Program, Graduate School of Arts and Sciences, Boston University, Boston, Massachusetts 02215. ^[1] New England Biolabs, Ipswich, Massachusetts 01938. ^[2] Biological Resource Center, Korea Research Institute of Bioscience and Biotechnology, Ipsin-gil, Jeongeup-si, Jeollabuk-do 56212, South Korea. ^[3] Center for Molecular Discovery, Boston University, Boston, Massachusetts 02215. ^[4] MCBB Graduate Program, Graduate School of Arts and Sciences, Boston University, Boston, Massachusetts 02215 uhansen@bu.edu.;Department of Biology, Boston University, Boston, Massachusetts 02215. ^[5]

关键词 SET8 cancer cytoskeleton lysine methyltransferase 5A (KMT5A)mammalian cells posttranslational modification (PTM)protein methylation transcription factor CP2 (TFCP2)transcription factor LSF tubulin

主题词动物(Animals);COS细胞(COS Cells);DNA结合蛋白质类(DNA-Binding Proteins);HEK293细胞(HEK293 Cells);组蛋白赖氨酸N-甲基转移酶(Histone-Lysine N-Methyltransferase);组蛋白类(Histones);人类(Humans);甲基化(Methylation);蛋白质结合(Protein Binding);重组融合蛋白质类(Recombinant Fusion Proteins);转录因子(Transcription Factors);微管蛋白(Tubulin)

DOI 10.1074/jbc.RA119.010951

PMID 32111740

发布时间 2024-07-28

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The Journal of biological chemistry

The Journal of biological chemistry

2020年295卷14期

4748-4759页

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