首页> Frontiers in oncology> Heterozygous p53-R280T Mutation Enhances the Oncogenicity of NPC Cells Through Activating PI3K-Akt Signaling Pathway.

Heterozygous p53-R280T Mutation Enhances the Oncogenicity of NPC Cells Through Activating PI3K-Akt Signaling Pathway.

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第一作者： Zhen-Qi,Qin

第一单位： Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, China.;Research Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University, Changsha, China.;The Higher Educational Key Laboratory for Cancer Proteomics and Translational Medicine of Hunan Province, Xiangya Hospital, Central South University, Changsha, China.

作者： Zhen-Qi,Qin ^[1] ; Qi-Guang,Li ^[2] ; Hong,Yi ^[2] ; Shan-Shan,Lu ^[2] ; Wei,Huang ^[2] ; Zhuo-Xian,Rong ^[2] ; Yao-Yun,Tang ^[3] ; Zhi-Qiang,Xiao ^[1]

作者单位： Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, China.;Research Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University, Changsha, China.;The Higher Educational Key Laboratory for Cancer Proteomics and Translational Medicine of Hunan Province, Xiangya Hospital, Central South University, Changsha, China. ^[1] Research Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University, Changsha, China.;The Higher Educational Key Laboratory for Cancer Proteomics and Translational Medicine of Hunan Province, Xiangya Hospital, Central South University, Changsha, China. ^[2] Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, China. ^[3]

关键词 Akt R280T mutation nasopharyngeal carcinoma oncogenicity p53

DOI 10.3389/fonc.2020.00104

PMID 32117754

发布时间 2020-09-28

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