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Ribosomal DNA copy number is associated with P53 status and levels of heavy metals in gastrectomy specimens from gastric cancer patients.

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第一作者： Lingfang,Feng

第一单位： Institute of Occupational Diseases, Zhejiang Academy of Medical Sciences, Hangzhou, China; Hangzhou Medical College, Hangzhou, China.

作者： Lingfang,Feng ^[1] ; Jing,Du ^[2] ; Chunji,Yao ^[3] ; Zhaoqiang,Jiang ^[1] ; Tao,Li ^[1] ; Quan,Zhang ^[4] ; Xinnian,Guo ^[1] ; Min,Yu ^[1] ; Hailing,Xia ^[1] ; Li,Shi ^[1] ; Junlin,Jia ^[5] ; Yan,Tong ^[6] ; Li,Ju ^[1] ; Jiaqi,Liu ^[1] ; Jianlin,Lou ^[7] ; Bernardo,Lemos ^[8]

作者单位： Institute of Occupational Diseases, Zhejiang Academy of Medical Sciences, Hangzhou, China; Hangzhou Medical College, Hangzhou, China. ^[1] Department of Gastroenterology, Zhejiang Provincial People's Hospital, Hangzhou, China; People's Hospital of Hangzhou Medical College, Hangzhou, China. ^[2] Institute of Hygiene, Zhejiang Academy of Medical Sciences, Hangzhou, China; Hangzhou Medical College, Hangzhou, China. ^[3] Key Laboratory of Microbial Technology for Industrial Pollution Control of Zhejiang Province, College of Environment, Zhejiang University of Technology, Hangzhou, China. ^[4] Center for Biostatistics, Bioinformatics and Big Data, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. ^[5] Affiliated Hangzhou First People's Hospital Zhejiang University School of Medicine, Hangzhou, China. ^[6] Institute of Occupational Diseases, Zhejiang Academy of Medical Sciences, Hangzhou, China; Hangzhou Medical College, Hangzhou, China. Electronic address: jianlinlou@163.com. ^[7] Department of Environmental Health, Harvard University T.H. Chan School of Public Health, Boston, USA. ^[8]

关键词 Carcinogenesis Gastric cancer Markers Metals rDNA

医学主题词 DNA拷贝数变异(DNA Copy Number Variations);DNA, 核糖体(DNA, Ribosomal);胃切除术(Gastrectomy);人类(Humans);金属, 重(Metals, Heavy);胃肿瘤(Stomach Neoplasms);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53)

DOI 10.1016/j.envint.2020.105593

PMID 32120062

发布时间 2020-11-20

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准确一般字义偏差语意偏离译文作用小提交