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首页> Molecules (Basel, Switzerland)> An Improved Synthesis of Key Intermediate to the Formation of Selected Indolin-2-Ones Derivatives Incorporating Ultrasound and Deep Eutectic Solvent (DES) Blend of Techniques, for Some Biological Activities and Molecular Docking Studies.

An Improved Synthesis of Key Intermediate to the Formation of Selected Indolin-2-Ones Derivatives Incorporating Ultrasound and Deep Eutectic Solvent (DES) Blend of Techniques, for Some Biological Activities and Molecular Docking Studies.

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作者： Mohd,Imran ^[1] ; Md Afroz,Bakht ^[2] ; Abida,Khan ^[1] ; Md Tauquir,Alam ^[1] ; El Hassane,Anouar ^[2] ; Mohammed B,Alshammari ^[2] ; Noushin,Ajmal ^[3] ; Archana,Vimal ^[4] ; Awanish,Kumar ^[4] ; Yassine,Riadi ^[5]

作者单位： Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Northern Border University, Rafha 91911, Saudi Arabia. ^[1] Department of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia. ^[2] Department of Basic Sciences and Humanities, Pratap University, Jaipur 303104, Rajasthan, India. ^[3] Department of Biotechnology, National Institute of Technology Raipur C. G., Raipur 49101, India. ^[4] Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia. ^[5]

关键词 DES DFT analgesic anti-inflammatory lipid peroxidation molecular docking thiazole-indole ulcerogenic ultrasound

主题词镇痛药(Analgesics);动物(Animals);消炎药, 非甾类(Anti-Inflammatory Agents, Non-Steroidal);环氧化酶2(Cyclooxygenase 2);环氧化酶2抑制剂(Cyclooxygenase 2 Inhibitors);女(雌)性(Female);吲哚类(Indoles);男(雄)性(Male);小鼠(Mice);构效关系(Structure-Activity Relationship)

DOI 10.3390/molecules25051118

PMID 32131536

发布时间 2020-12-14

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Molecules (Basel, Switzerland)

Molecules (Basel, Switzerland)

2020年25卷5期

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