Methylation of SRD5A2 promoter predicts a better outcome for castration-resistant prostate cancer patients undergoing androgen deprivation therapy.
作者:
主题词
3-羰基-5-α-类固醇4-脱氢酶(3-Oxo-5-alpha-Steroid 4-Dehydrogenase);5-α还原酶抑制剂(5-alpha Reductase Inhibitors);雄甾烯类(Androstenes);DNA甲基化(DNA Methylation);后成说, 遗传(Epigenesis, Genetic);人类(Humans);男(雄)性(Male);膜蛋白质类(Membrane Proteins);预后(Prognosis);启动区, 遗传(Promoter Regions, Genetic);治疗结果(Treatment Outcome)
DOI
10.1371/journal.pone.0229754
PMID
32134978
发布时间
2024-07-27
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PloS one
e0229754页
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