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Unprecedented Potential for Neural Drug Discovery Based on Self-Organizing hiPSC Platforms.

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第一作者： Agustín,Cota-Coronado

第一单位： Medical and Pharmaceutical Biotechnology, Center for Research and Assistance in Technology and Design of the State of Jalisco, CIATEJ A.C, 800 Normalistas, Colinas de La Normal, Guadalajara 44270, Jalisco, Mexico.;The Florey Institute of Neuroscience and Mental Health, 30 Royal Parade, Parkville, VIC 3052, Australia.

作者： Agustín,Cota-Coronado ^[1] ; Jennifer C,Durnall ^[2] ; Néstor Fabián,Díaz ^[3] ; Lachlan H,Thompson ^[2] ; N Emmanuel,Díaz-Martínez ^[4]

作者单位： Medical and Pharmaceutical Biotechnology, Center for Research and Assistance in Technology and Design of the State of Jalisco, CIATEJ A.C, 800 Normalistas, Colinas de La Normal, Guadalajara 44270, Jalisco, Mexico.;The Florey Institute of Neuroscience and Mental Health, 30 Royal Parade, Parkville, VIC 3052, Australia. ^[1] The Florey Institute of Neuroscience and Mental Health, 30 Royal Parade, Parkville, VIC 3052, Australia. ^[2] Departamento de Fisiología y Desarrollo Celular, Instituto Nacional de Perinatología, Mexico City 11000, Mexico. ^[3] Medical and Pharmaceutical Biotechnology, Center for Research and Assistance in Technology and Design of the State of Jalisco, CIATEJ A.C, 800 Normalistas, Colinas de La Normal, Guadalajara 44270, Jalisco, Mexico. ^[4]

关键词 3D culture drug-discovery platforms hiPSCs high-throughput screening self-assembly organoids

医学主题词细胞培养技术(Cell Culture Techniques);药物发现(Drug Discovery);人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);类器官(Organoids)

DOI 10.3390/molecules25051150

PMID 32143423

发布时间 2020-12-14

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