Potential strategy for assessing QT/QTc interval for drugs that produce rapid changes in heart rate: Electrocardiographic assessment of the effects of intravenous remimazolam on cardiac repolarization.

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作者： Robert B,Kleiman ^[1] ; Borje,Darpo ^[1] ; Michael,Thorn ^[2] ; Thomas,Stoehr ^[3] ; Frank,Schippers ^[3]

作者单位： eResearch Technology, Philadelphia, PA, USA. ^[1] Statistical Resources, Chapel Hill, NC, USA. ^[2] Paion Germany GmbH, Aachen, Germany. ^[3]

关键词 intravenous drug administration, QT interval, QT-RR hysteresis

主题词苯二氮|艹卓|类(Benzodiazepines);剂量效应关系, 药物(Dose-Response Relationship, Drug);双盲法(Double-Blind Method);心电描记术(Electrocardiography);心率(Heart Rate);人类(Humans);药用制剂(Pharmaceutical Preparations)

DOI 10.1111/bcp.14270

PMID 32144789

发布时间 2021-07-02

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British journal of clinical pharmacology

2020年86卷8期

1600-1609页

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Potential strategy for assessing QT/QTc interval for drugs that produce rapid changes in heart rate: Electrocardiographic assessment of the effects of intravenous remimazolam on cardiac repolarization.

British journal of clinical pharmacology

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British journal of clinical pharmacology

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Potential strategy for assessing QT/QTc interval for drugs that produce rapid changes in heart rate: Electrocardiographic assessment of the effects of intravenous remimazolam on cardiac repolarization.

British journal of clinical pharmacology

相似文献

British journal of clinical pharmacology

相关期刊

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