Exendin-4 protects the hearts of rats from ischaemia/reperfusion injury by boosting antioxidant levels and inhibition of JNK/p<sup>66</sup> Shc/NADPH axis.

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作者： Refaat A,Eid ^[1] ; Mohamed Samir Ahmed,Zaki ^[2] ; Muhammad,Alaa Eldeen ^[3] ; Majed M,Alshehri ^[4] ; Ayed A,Shati ^[5] ; Attalla Farag,El-Kott ^[6]

作者单位： Department of Pathology, College of Medicine, King Khalid University, Abha, Saudi Arabia. ^[1] Department of Anatomy, College of Medicine, King Khalid University, Abha, Saudi Arabia.;Department of Histology, Faculty of Medicine, Zagazig University, Zagazig, Egypt. ^[2] Biology Department, Physiology Section, Faculty of Science, Zagazig University, Zagazig, Egypt. ^[3] Central laboratories, King Faisal Medical City (southern region), Abha, Saudi Arabia. ^[4] Department of Child Health, College of Medicine, King Khalid University, Abha, Saudi Arabia. ^[5] Department of Biology, College of Science, King Khalid University, Abha, Saudi Arabia.;Department of Zoology, Faculty of Science, Damanhour University, Damanhour, Egypt. ^[6]

关键词 Exendin-4 Exendin-4 inhibits JNN/P66Shc/NADPH in cardiac I/R injury JNK heart ischaemia oxidative stress p66Shc reperfusion

DOI 10.1111/1440-1681.13299

PMID 32149419

发布时间 2024-07-24

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