mGluR5 receptor availability is associated with lower levels of negative symptoms and better cognition in male patients with chronic schizophrenia.

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作者： Cláudia,Régio Brambilla ^[1] ; Tanja,Veselinović ^[2] ; Ravichandran,Rajkumar ^[2] ; Jörg,Mauler ^[1] ; Linda,Orth ^[2] ; Andrej,Ruch ^[3] ; Shukti,Ramkiran ^[1] ; Karsten,Heekeren ^[1] ; Wolfram,Kawohl ^[2] ; Christine,Wyss ^[2] ; Elena Rota,Kops ^[1] ; Jürgen,Scheins ^[2] ; Lutz,Tellmann ^[4] ; Frank,Boers ^[4] ; Bernd,Neumaier ^[4] ; Johannes,Ermert ^[1] ; Hans,Herzog ^[1] ; Karl-Josef,Langen ^[1] ; N,Jon Shah ^[1] ; Christoph,Lerche ^[5] ; Irene,Neuner ^[5]

作者单位： INM-4, Forschungszentrum Jülich GmbH, Wilhelm-Johnen-Straße, Institute of Neuroscience and Medicine, Jülich, Germany. ^[1] Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Aachen, Germany. ^[2] JARA - BRAIN - Translational Medicine, Aachen, Germany. ^[3] Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital of Psychiatry, Zürich, Switzerland. ^[4] INM-5, Forschungszentrum Jülich GmbH, Wilhelm-Johnen-Straße, Institute of Neuroscience and Medicine, Jülich, Germany. ^[5] Department of Nuclear Medicine, RWTH Aachen University, Aachen, Germany. ^[6] INM-11, Forschungszentrum Jülich GmbH, Wilhelm-Johnen-Straße, Institute of Neuroscience and Medicine, Jülich, Germany. ^[7] Department of Neurology, RWTH Aachen University, Aachen, Germany. ^[8]

关键词 chronic schizophrenia cognition mGluR5 receptor negative symptoms positron emission tomography