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首页> eLife> HIPK4 is essential for murine spermiogenesis.

HIPK4 is essential for murine spermiogenesis.

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作者： J Aaron,Crapster ^[1] ; Paul G,Rack ^[1] ; Zane J,Hellmann ^[1] ; Austen D,Le ^[1] ; Christopher M,Adams ^[2] ; Ryan D,Leib ^[2] ; Joshua E,Elias ^[3] ; John,Perrino ^[4] ; Barry,Behr ^[5] ; Yanfeng,Li ^[6] ; Jennifer,Lin ^[6] ; Hong,Zeng ^[6] ; James K,Chen ^[1]

作者单位： Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, United States. ^[1] Stanford University Mass Spectrometry, Stanford University, Stanford, United States. ^[2] Chan Zuckerberg Biohub, Stanford University, Stanford, United States. ^[3] Cell Science Imaging Facility, Stanford University School of Medicine, Stanford, United States. ^[4] Department of Obstetrics and Gynecology, Reproductive Endocrinology and Infertility, Stanford University School of Medicine, Stanford, United States. ^[5] Transgenic, Knockout, and Tumor Model Center, Stanford University School of Medicine, Stanford, United States. ^[6] Department of Developmental Biology, Stanford University School of Medicine, Stanford, United States. ^[7] Department of Chemistry, Stanford University, Stanford, United States. ^[8]

关键词 HIPK4 cell biology cytoskeleton developmental biology fertility kinase mouse spermiogenesis

主题词顶体(Acrosome);肌动蛋白类(Actins);动物(Animals);生育力(Fertility);荧光抗体技术(Fluorescent Antibody Technique);基因表达调控, 发育期(Gene Expression Regulation, Developmental);男(雄)性(Male);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);模型, 生物学(Models, Biological);突变(Mutation);表型(Phenotype);蛋白质结合(Protein Binding);信号传导(Signal Transduction);精细胞(Spermatids);精子发生(Spermatogenesis);精子(Spermatozoa)

DOI 10.7554/eLife.50209

PMID 32163033

发布时间 2024-04-23

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