Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells.

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作者： Miseon,Lee ^[1] ; Basudeb,Maji ^[1] ; Debasish,Manna ^[2] ; Sevim,Kahraman ^[1] ; Ruth M,Elgamal ^[2] ; Jonnell,Small ^[3] ; Praveen,Kokkonda ^[4] ; Amedeo,Vetere ^[1] ; Jacob M,Goldberg ^[2] ; Stephen J,Lippard ^[1] ; Rohit N,Kulkarni ^[5] ; Bridget K,Wagner ^[1] ; Amit,Choudhary ^[1]

作者单位： Chemical Biology and Therapeutics Science, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States. ^[1] Divisions of Renal Medicine and Engineering, Brigham and Women's Hospital, Boston, Massachusetts 02115, United States. ^[2] Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, Massachusetts 02215, United States. ^[3] Harvard Stem Cell InstituteHarvard Medical School, Cambridge, Massachusetts 02138, United States. ^[4] Chemical Biology Program, Harvard University, Cambridge, Massachusetts 02138, United States. ^[5] Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States. ^[6]

主题词 B-淋巴细胞(B-Lymphocytes);催化作用(Catalysis);糖尿病, 1型(Diabetes Mellitus, Type 1);糖尿病, 2型(Diabetes Mellitus, Type 2);人类(Humans);锌(Zinc)

DOI 10.1021/jacs.0c00099

PMID 32175731

发布时间 2023-06-17

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