Biallelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells.
作者:
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞周期(Cell Cycle);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因敲除技术(Gene Knockout Techniques);人类(Humans);小鼠(Mice);小鼠, SCID(Mice, SCID);多发性骨髓瘤(Multiple Myeloma);核苷酸基转移酶类(Nucleotidyltransferases);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);磷酰化(Phosphorylation);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);吡唑类(Pyrazoles);信号传导(Signal Transduction);噻吩类(Thiophenes)
DOI
10.1111/cas.14386
PMID
32176823
发布时间
2020-06-01
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Cancer science
1663-1675页
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