Tuning the Polymorphism of the Anti-VEGF G-rich V7t1 Aptamer by Covalent Dimeric Constructs.

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作者： Claudia,Riccardi ^[1] ; Domenica,Musumeci ^[1] ; Chiara,Platella ^[2] ; Rosa,Gaglione ^[1] ; Angela,Arciello ^[1] ; Daniela,Montesarchio ^[1]

作者单位： Department of Chemical Sciences, University of Naples Federico II, Via Cintia 21, I-80126, Napoli, Italy. ^[1] Institute of Biostructures and Bioimages (IBB), CNR, Via Mezzocannone 16, I-80134 Napoli, Italy. ^[2] National Institute of Biostructures and Biosystems (INBB), 00136 Rome, Italy. ^[3]

关键词 G-quadruplexes V7t1 VEGF165 aptamers biophysical characterization covalent dimers

主题词适体, 核苷(Aptamers, Nucleotide);细胞增殖(Cell Proliferation);G四链体(G-Quadruplexes);人类(Humans);蛋白质结合(Protein Binding);血管内皮生长因子A(Vascular Endothelial Growth Factor A)

DOI 10.3390/ijms21061963

PMID 32183039

发布时间 2020-12-01

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