换一批
换一批Hearing impairment-associated KARS mutations lead to defects in aminoacylation of both cytoplasmic and mitochondrial tRNA<sup>Lys</sup>.
第一作者：
Yong,Wang
第一单位：
State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.;School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
作者：
主题词
氨酰基tRNA合成酶类(Amino Acyl-tRNA Synthetases);氨基酰化(Aminoacylation);碱基序列(Base Sequence);催化域(Catalytic Domain);细胞质(Cytoplasm);基因表达调控(Gene Expression Regulation);听觉丧失(Hearing Loss);人类(Humans);线粒体(Mitochondria);模型, 分子(Models, Molecular);突变(Mutation);蛋白质生物合成(Protein Biosynthesis);蛋白质构象(Protein Conformation);RNA, 转移, 赖氨酸(RNA, Transfer, Lys);重组蛋白质类(Recombinant Proteins);酿酒酵母菌(Saccharomyces cerevisiae);酿酒酵母蛋白质类(Saccharomyces cerevisiae Proteins);转染(Transfection)
DOI
10.1007/s11427-019-1619-x
PMID
32189241
发布时间
2020-10-27
- 浏览0
Science China. Life sciences
2020年63卷8期
1227-1239页
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