Zygophyllum album leaves extract prevented hepatic fibrosis in rats, by reducing liver injury and suppressing oxidative stress, inflammation, apoptosis and the TGF-β1/Smads signaling pathways. Exploring of bioactive compounds using HPLC-DAD-ESI-QTOF-MS/MS.-论文-万方医学网

作者： Anouar,Feriani ^[1] ; Meriam,Tir ^[2] ; Ana María,Gómez-Caravaca ^[3] ; María,Del Mar Contreras ^[3] ; Amani,Taamalli ^[4] ; Antonio,Segura-Carretero ^[5] ; Lakhdar,Ghazouani ^[3] ; Afoua,Mufti ^[1] ; Nizar,Tlili ^[1] ; Abdelfattah,El Feki ^[6] ; Abdel Halim,Harrath ^[7] ; Mohamed Salah,Allagui ^[8]

作者单位： Research Unit of Macromolecular Biochemistry and Genetics, Faculty of Sciences of Gafsa, 2112, Gafsa, Tunisia. ^[1] Laboratoire D'Ecologie, de Biologie Et de Physiologie Des Organismes Aquatiques, LR18ES41, Faculté Des Sciences de Tunis, Université Tunis EL Manar, 2092, Tunis, Tunisia. tirmeriam@yahoo.fr. ^[2] Department of Analytical Chemistry, University of Granada, Avda. Fuentenueva S/N, 18071, Granada, Spain. ^[3] Department of Chemical, Environmental and Material Engineering, University of Jaén, Campus Las Lagunillas, s/n, 23071, Jaén, Spain. ^[4] Laboratory of Olive Biotechnology, Center of Biotechnology of Borj-Cédria, BP. 901, 2050, Hammam-Lif, Tunisia. ^[5] Institut Supérieur des Sciences et Technologies de l'Environnement, ISSTE de Borj Cédria, Université de Carthage, 2050, Hammam-Lif, Tunisia. ^[6] Faculté Des Sciences de Tunis (UR13/ES25), Université Tunis El-Manar, 2092, Tunis, Tunisia. ^[7] Laboratory of Animal Ecophysiology, Faculty of Science of Sfax, 3018, Sfax, Tunisia. ^[8] Department of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia. ^[9]

主题词动物(Animals);消炎药(Anti-Inflammatory Agents);抗氧化剂(Antioxidants);细胞凋亡(Apoptosis);色谱法, 高压液相(Chromatography, High Pressure Liquid);细胞因子类(Cytokines);肝星状细胞(Hepatic Stellate Cells);炎症(Inflammation);肝(Liver);肝硬化(Liver Cirrhosis);男(雄)性(Male);氧化性应激(Oxidative Stress);植物提取物(Plant Extracts);植物叶(Plant Leaves);预防和防护用药(Protective Agents);大鼠(Rats);大鼠, Wistar(Rats, Wistar);信号传导(Signal Transduction);Smad蛋白质类(Smad Proteins);串联质谱法(Tandem Mass Spectrometry);转化生长因子β1(Transforming Growth Factor beta1);霸王属(Zygophyllum)

DOI 10.1007/s10787-020-00700-y

PMID 32206981

发布时间 2021-07-13

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Zygophyllum album leaves extract prevented hepatic fibrosis in rats, by reducing liver injury and suppressing oxidative stress, inflammation, apoptosis and the TGF-β1/Smads signaling pathways. Exploring of bioactive compounds using HPLC-DAD-ESI-QTOF-MS/MS.

Inflammopharmacology

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Inflammopharmacology

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Zygophyllum album leaves extract prevented hepatic fibrosis in rats, by reducing liver injury and suppressing oxidative stress, inflammation, apoptosis and the TGF-β1/Smads signaling pathways. Exploring of bioactive compounds using HPLC-DAD-ESI-QTOF-MS/MS.

Inflammopharmacology

相似文献

Inflammopharmacology

相关期刊

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