Type 5 17-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3) inhibition and potential anti-proliferative activity of cholest-4-ene-3,6-dione in MCF-7 breast cancer cells.
第一作者:
Veeresh Kumar,Sali
第一单位:
Natural Products Research Laboratory, Department of Biotechnology, Pondicherry University, Puducherry 605014, India.
作者:
医学主题词
抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);细胞周期(Cell Cycle);细胞增殖(Cell Proliferation);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);酶抑制剂(Enzyme Inhibitors);人类(Humans);分子结构(Molecular Structure);孕烯二酮类(Pregnenediones);构效关系(Structure-Activity Relationship)
DOI
10.1016/j.steroids.2020.108638
PMID
32209376
发布时间
2021-02-09
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