换一批Diabetes as a risk factor for Alzheimer's disease in the Middle East and its shared pathological mediators.
第一作者：
Richard L,Jayaraj
第一单位：
Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates.
作者：
关键词
AAV, Adeno-associated virusABCA1, ATP binding cassette subfamily A member 1AD, Alzheimer’s diseaseADAMTS9, ADAM Metallopeptidase With Thrombospondin Type 1 Motif 9AGPAT1, 1-acyl-sn-glycerol-3-phosphate acyltransferase alphaAlzheimer’s diseaseAnti-diabetic drugsApoE, Apolipoprotein EArab populationAβ, Amyloid-betaBACE1, Beta-secretase 1BBB, Blood-Brain BarrierBMI, Body mass indexCALR, calreticulin geneCIP2A, Cancerous Inhibitor Of Protein Phosphatase 2ACOX-2, Cyclooxygenase 2CSF, Cerebrospinal fluidDM, Diabetes mellitusDUSP9, Dual Specificity Phosphatase 9Diabetes mellitusECE-1, Endotherin converting enzyme 1FDG-PET, Fluorodeoxyglucose- positron emission tomographyFRMD4A, FERM Domain Containing 4AFTO, Fat Mass and Obesity Associated GeneGLP-1, Glucagon like peptideGNPDA2, Glucosamine-6-phosphate deaminase 2GSK-3β, Glycogen synthase kinase 3 betaIDE, Insulin degrading enzymeIGF-1, Insulin-like growth factor 1IR, Insulin receptorIR, Insulin resistanceInsulin signalingLPA, Lipophosphatidic acidMC4R, Melanocortin 4 receptorMCI, Myocardial infarctionMENA, Middle East North AfricanMG-H1, Methylglyoxal-hydroimidazolone isomer trifluoroactic acid saltMRI, Magnetic resonance imagingNDUFS3, NADH:Ubiquinone Oxidoreductase Core Subunit S3NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cellsNFT, Neurofibrillary tanglesNOTCH4, Neurogenic locus notch homolog protein 4PI3K, Phosphoinositide-3PP2A, Protein phosphatase 2PPAR-γ2, Peroxisome proliferator-activated receptor gamma 2Pit-PET, Pittsburgh compound B- positron emission tomographyRAB1A, Ras-related protein 1ASORT, SortilinSTZ, StreptozotocinT1DM, Type 1 Diabetes MellitusT2DM, Type 2 Diabetes MellitusTCF7L2, Transcription Factor 7 Like 2TFAP2B, Transcription Factor AP-2 Beta
DOI
10.1016/j.sjbs.2019.12.028
PMID
32210695
发布时间
2023-11-03
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