Synthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory Viruses.

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作者： Valeria,Francesconi ^[1] ; Elena,Cichero ^[1] ; Silvia,Schenone ^[1] ; Lieve,Naesens ^[2] ; Michele,Tonelli ^[1]

作者单位： Dipartimento di Farmacia, Università di Genova, Viale Benedetto XV 3, 16132 Genova, Italy. ^[1] Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium. ^[2]

关键词 (thio)semicarbazone-based benzimidazoles anti-RSV activity anti-coronavirus activity anti-influenza activity hydrazone-based benzimidazoles molecular modelling studies

主题词动物(Animals);抗病毒药(Antiviral Agents);苯咪唑类(Benzimidazoles);细胞, 培养的(Cells, Cultured);冠状病毒属(Coronavirus);狗(Dogs);人类(Humans);流感病毒A型(Influenza A virus);微生物敏感性试验(Microbial Sensitivity Tests);模型, 分子(Models, Molecular);呼吸道合胞体病毒, 人(Respiratory Syncytial Virus, Human);呼吸道感染(Respiratory Tract Infections);缩氨基脲类(Semicarbazones);构效关系(Structure-Activity Relationship)

DOI 10.3390/molecules25071487

PMID 32218301

发布时间 2020-09-21

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Molecules (Basel, Switzerland)

2020年25卷7期

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Synthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory Viruses.

Molecules (Basel, Switzerland)

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Synthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory Viruses.

Molecules (Basel, Switzerland)

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Molecules (Basel, Switzerland)

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