Activation of α7 Nicotinic Acetylcholine Receptor Upregulates HLA-DR and Macrophage Receptors: Potential Role in Adaptive Immunity and in Preventing Immunosuppression.

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作者： Andrei E,Siniavin ^[1] ; Maria A,Streltsova ^[2] ; Denis S,Kudryavtsev ^[3] ; Irina V,Shelukhina ^[3] ; Yuri N,Utkin ^[3] ; Victor I,Tsetlin ^[4]

作者单位： Department of Molecular Neuroimmune Signalling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.;N.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow 123098, Russia. ^[1] Department of Immunology, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia. ^[2] Department of Molecular Neuroimmune Signalling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia. ^[3] Department of Molecular Neuroimmune Signalling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.;Institute of Engineering Physics for Biomedicine, National Research Nuclear University, Moscow 115409, Russia. ^[4]

关键词 adaptive immunity immunosuppression inflammation innate immunity macrophages α7 nAChR

主题词适应性免疫(Adaptive Immunity);苯甲酰胺类(Benzamides);细胞因子类(Cytokines);HLA-DR抗原(HLA-DR Antigens);人类(Humans);免疫耐受(Immune Tolerance);白细胞介素10(Interleukin-10);脂多糖类(Lipopolysaccharides);巨噬细胞(Macrophages);烟碱激动剂(Nicotinic Agonists);膜片钳术(Patch-Clamp Techniques)

DOI 10.3390/biom10040507

PMID 32230846

发布时间 2024-07-29

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Biomolecules

2020年10卷4期

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Activation of α7 Nicotinic Acetylcholine Receptor Upregulates HLA-DR and Macrophage Receptors: Potential Role in Adaptive Immunity and in Preventing Immunosuppression.

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Activation of α7 Nicotinic Acetylcholine Receptor Upregulates HLA-DR and Macrophage Receptors: Potential Role in Adaptive Immunity and in Preventing Immunosuppression.

Biomolecules

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