换一批Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications.
第一作者：
Juan,Carrillo-Reixach
第一单位：
Childhood Liver Oncology Group, Germans Trias i Pujol Research Institute (IGTP), Program for Predictive and Personalized Medicine of Cancer (PMPPC), Badalona, Spain.
作者：
Juan,Carrillo-Reixach [1]
;
Laura,Torrens [2]
;
Marina,Simon-Coma [3]
;
Laura,Royo [1]
;
Montserrat,Domingo-Sàbat [1]
;
Jordi,Abril-Fornaguera [2]
;
Nicholas,Akers [4]
;
Margarita,Sala [5]
;
Sonia,Ragull [1]
;
Magdalena,Arnal [6]
;
Núria,Villalmanzo [7]
;
Stefano,Cairo [8]
;
Alberto,Villanueva [9]
;
Roland,Kappler [10]
;
Marta,Garrido [11]
;
Laura,Guerra [12]
;
Constantino,Sábado [13]
;
Gabriela,Guillén [14]
;
Mar,Mallo [15]
;
David,Piñeyro [16]
;
María,Vázquez-Vitali [1]
;
Olga,Kuchuk [17]
;
María Elena,Mateos [18]
;
Gema,Ramírez [19]
;
Manuel López,Santamaría [20]
;
Yasmina,Mozo [21]
;
Aroa,Soriano [22]
;
Michael,Grotzer [23]
;
Sophie,Branchereau [24]
;
Nagore García,de Andoin [25]
;
Blanca,López-Ibor [26]
;
Ricardo,López-Almaraz [27]
;
José Antonio,Salinas [28]
;
Bárbara,Torres [29]
;
Francisco,Hernández [20]
;
José Javier,Uriz [25]
;
Monique,Fabre [30]
;
Julià,Blanco [31]
;
Claudia,Paris [32]
;
Viera,Bajčiová [33]
;
Geneviève,Laureys [34]
;
Helena,Masnou [35]
;
Ariadna,Clos [35]
;
Cristina,Belendez [36]
;
Catherine,Guettier [24]
;
Lauro,Sumoy [16]
;
Ramón,Planas [37]
;
Mireia,Jordà [38]
;
Lara,Nonell [6]
;
Piotr,Czauderna [39]
;
Bruce,Morland [40]
;
Daniela,Sia [17]
;
Bojan,Losic [41]
;
Marie Annick,Buendia [42]
;
Maria Rosa,Sarrias [43]
;
Josep M,Llovet [44]
;
Carolina,Armengol [45]
作者单位：
Childhood Liver Oncology Group, Germans Trias i Pujol Research Institute (IGTP), Program for Predictive and Personalized Medicine of Cancer (PMPPC), Badalona, Spain.
[1]
Mount Sinai Liver Cancer Program, Divisions of Liver Diseases, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA; Translational research in Hepatic Oncology, Liver Unit, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.
[2]
Childhood Liver Oncology Group, Germans Trias i Pujol Research Institute (IGTP), Program for Predictive and Personalized Medicine of Cancer (PMPPC), Badalona, Spain; CIBER, Hepatic and Digestive Diseases, Barcelona, Spain.
[3]
Translational research in Hepatic Oncology, Liver Unit, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic, Universitat de Barcelona, Barcelona, Spain; Department of Genetics and Genomic Sciences, The Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, USA.
[4]
CIBER, Hepatic and Digestive Diseases, Barcelona, Spain; Gastroenterology Department, Hospital Universitari Germans Trias i Pujol Hospital, Badalona, Spain; Gastroenterology Department, Hospital Universitari Josep Trueta, Girona, Spain.
[5]
MARGenomics, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.
[6]
PMPPC, IGTP, Badalona, Spain.
[7]
XenTech, Evry, France; Instituto di Ricerca Pediatrica, Corso Stati Uniti 4, Padova, Italy.
[8]
Chemoresistance and Predictive Factors Group, Program Against Cancer Therapeutic Resistance, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute, L'Hospitalet del Llobregat, Barcelona, Spain.
[9]
Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Lindwurmstr. 2a, 80337 Munich, Germany.
[10]
Hospital Vall d'Hebron, Pathology Department, Barcelona, Spain.
[11]
University Hospital La Paz, Pathology Department, Madrid, Spain.
[12]
Hospital Vall d'Hebron, Pediatric Oncology Department, Barcelona, Spain.
[13]
Hospital Vall d'Hebron, Pediatric Surgery Department, Barcelona, Spain.
[14]
MDS Research Group, Josep Carreras Leukaemia Research Institute, ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain.
[15]
High Content Genomics and Bioinformatics Unit, PMPPC, IGTP, Badalona, Spain.
[16]
Mount Sinai Liver Cancer Program, Divisions of Liver Diseases, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
[17]
Pediatric Oncology Unit, Department of Pediatrics, University Hospital Reina Sofía, Córdoba, Spain.
[18]
University Hospital Universitario Virgen del Rocío, Pediatric Oncology Department, Sevilla, Spain.
[19]
University Hospital La Paz, Pediatric Surgery Department, Madrid, Spain.
[20]
University Hospital La Paz, Pediatric Oncology Department, Madrid, Spain.
[21]
Biomedical Research in Cancer Stem Cells Group, Pathology Department, Institut de Recerca Hospital Vall d'Hebron (VHIR), Barcelona, Spain.
[22]
Department of Pediatric Oncology, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
[23]
Bicêtre Hospital, Le Kremlin-Bicêtre, France.
[24]
Pediatric Oncology, Hospital Universitario Donostia, Doctor Begiristain Kalea, 117, 20080, Donostia, Spain.
[25]
Department of Pediatric Hematology and Oncology, HM Montepríncipe Hospital, Boadilla del Monte, Madrid, Spain.
[26]
Pediatric Oncology and Hematology, Hospital Universitario Cruces, Bilbao, Spain.
[27]
Division of Hematology-Oncology, Department of Pediatrics, Hospital Universitari Son Espases, Palma de Mallorca, Spain.
[28]
Medical Oncology Department, Pediatric Oncology Department, University Hospital La Fe, Valencia, Spain.
[29]
Department of Pathology, Hôpital Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, and Université Paris Descartes, Paris, France.
[30]
IrsiCaixa AIDS Research Institute, IGTP, Badalona, Catalonia, Spain; University of Vic - Central University of Catalonia, Vic, Spain.
[31]
Stem Cell Transplant Unit, Hospital Luis Calvo Mackenna, Santiago, Chile.
[32]
Department of Pediatric Oncology, Childrens University Hospital Brno, Brno, Czech.
[33]
Department of Pediatric Hematology, Oncology and Hematopoietic Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.
[34]
Gastroenterology Department, Hospital Universitari Germans Trias i Pujol Hospital, Badalona, Spain.
[35]
Oncohematology Service, Hospital Gregorio Marañón, Madrid, Spain.
[36]
CIBER, Hepatic and Digestive Diseases, Barcelona, Spain; Gastroenterology Department, Hospital Universitari Germans Trias i Pujol Hospital, Badalona, Spain.
[37]
PMPPC, IGTP, Badalona, Spain; Consortium for the Study of Thyroid Cancer, CECaT, Barcelona, Spain.
[38]
Department of Surgery and Urology for Children and Adolescents, Medical University of Gdansk, Gdansk, Poland.
[39]
Department of Oncology, Birmingham Women's and Children's Hospital, Birmingham, UK.
[40]
Department of Genetics and Genomic Sciences, The Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, USA; Graduate School of Biomedical Sciences, One Gustave L. Levy Place, Box 1022, New York, NY; Tisch Cancer Institute, Cancer Immunology Program, Icahn School of Medicine at Mount Sinai, New York, NY; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY.
[41]
INSERM, UMR 1193, Paul-Brousse Hospital, Hepatobiliary Centre, Villejuif, France.
[42]
CIBER, Hepatic and Digestive Diseases, Barcelona, Spain; Innate Immunity Group, IGTP, Badalona, Spain.
[43]
Mount Sinai Liver Cancer Program, Divisions of Liver Diseases, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA; Translational research in Hepatic Oncology, Liver Unit, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic, Universitat de Barcelona, Barcelona, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.
[44]
Childhood Liver Oncology Group, Germans Trias i Pujol Research Institute (IGTP), Program for Predictive and Personalized Medicine of Cancer (PMPPC), Badalona, Spain; CIBER, Hepatic and Digestive Diseases, Barcelona, Spain. Electronic address: carmengol@igtp.cat.
[45]
医学主题词
钙结合蛋白质类(Calcium-Binding Proteins);胆碱激酶(Choline Kinase);DNA甲基化(DNA Methylation);药物发现(Drug Discovery);后成说, 遗传(Epigenesis, Genetic);女(雌)性(Female);基因表达谱(Gene Expression Profiling);肝胚细胞瘤(Hepatoblastoma);高通量筛选分析(High-Throughput Screening Assays);人类(Humans);婴儿(Infant);肝肿瘤(Liver Neoplasms);男(雄)性(Male);膜蛋白质类(Membrane Proteins);肿瘤蛋白质类(Neoplasm Proteins);预后(Prognosis);危险性评估(Risk Assessment);β连环素(beta Catenin)
DOI
10.1016/j.jhep.2020.03.025
PMID
32240714
发布时间
2025-09-23
- 浏览4
Journal of hepatology
Journal of hepatology
328-341页
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