SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells.-论文-万方医学网

第一作者： Soeren,Lukassen

第一单位： Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.;Center for Digital Health, Berlin Institute of Health (BIH), Berlin, Germany.

作者： Soeren,Lukassen ^[1] ; Robert Lorenz,Chua ^[1] ; Timo,Trefzer ^[1] ; Nicolas C,Kahn ^[2] ; Marc A,Schneider ^[3] ; Thomas,Muley ^[3] ; Hauke,Winter ^[4] ; Michael,Meister ^[3] ; Carmen,Veith ^[5] ; Agnes W,Boots ^[6] ; Bianca P,Hennig ^[1] ; Michael,Kreuter ^[7] ; Christian,Conrad ^[8] ; Roland,Eils ^[9]

作者单位： Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.;Center for Digital Health, Berlin Institute of Health (BIH), Berlin, Germany. ^[1] Department of Pneumology and Respiratory Critical Care Medicine, Center for interstitial and rare lung diseases, Thoraxklinik, Heidelberg University Hospital, Heidelberg, Germany.;Translational Lung Research Center Heidelberg (TLRC), Member of the German Center for Lung Research (DZL), Heidelberg, Germany. ^[2] Translational Lung Research Center Heidelberg (TLRC), Member of the German Center for Lung Research (DZL), Heidelberg, Germany.;Translational Research Unit, Thoraxklinik, Heidelberg University Hospital, Heidelberg, Germany. ^[3] Translational Lung Research Center Heidelberg (TLRC), Member of the German Center for Lung Research (DZL), Heidelberg, Germany.;Department of Thoracic Surgery, Thoraxklinik, Heidelberg University Hospital, Heidelberg, Germany. ^[4] Division of Redox Regulation, German Cancer Research Center (DKFZ) , Heidelberg, Germany. ^[5] Faculty of Health, Medicine and Life Sciences, Department of Pharmacology and Toxicology, NUTRIM School of Nutrition, Translational Research and Metabolism, Maastricht University, Maastricht, the Netherlands. ^[6] Department of Pneumology and Respiratory Critical Care Medicine, Center for interstitial and rare lung diseases, Thoraxklinik, Heidelberg University Hospital, Heidelberg, Germany. ^[7] Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. ^[8] Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.;Center for Digital Health, Berlin Institute of Health (BIH), Berlin, Germany.;Health Data Science Unit, Heidelberg University Hospital and BioQuant, Heidelberg, Germany. ^[9]

医学主题词成年人(Adult);衰老(Aging);支气管(Bronchi);细胞, 培养的(Cells, Cultured);慢性病(Chronic Disease);冠状病毒感染(Coronavirus Infections);上皮细胞(Epithelial Cells);女(雌)性(Female);基因表达(Gene Expression);基因表达谱(Gene Expression Profiling);德国(Germany);杯状细胞(Goblet Cells);人类(Humans);肺(Lung);男(雄)性(Male);中年人(Middle Aged);疾病大流行(Pandemics);肽基二肽酶A(Peptidyl-Dipeptidase A);肺炎, 病毒性(Pneumonia, Viral);参考标准(Reference Standards);序列分析, RNA(Sequence Analysis, RNA);丝氨酸内肽酶类(Serine Endopeptidases);性征(Sex Characteristics);单细胞分析(Single-Cell Analysis);吸烟(Smoking);组织库(Tissue Banks)

DOI 10.15252/embj.20105114

PMID 32246845

发布时间 2023-11-11

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SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells.

The EMBO journal

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SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells.

The EMBO journal

相似文献

同项目论文

The EMBO journal

相关期刊

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