Dysregulation of trophic factors contributes to diabetic retinopathy in the Ins2<sup>Akita</sup> mouse.

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作者： Rute S,Araújo ^[1] ; Maria S,Silva ^[2] ; Daniela F,Santos ^[3] ; Gabriela A,Silva ^[4]

作者单位： CEDOC - Chronic Diseases Research Center, NOVA Medical School, Universidade Nova de Lisboa, Campo Mártires da Pátria 130, 1169-056, Lisboa, Portugal; Bioengineering- Cell Therapies and Regenerative Medicine PhD Program, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001, Lisboa, Portugal. ^[1] CEDOC - Chronic Diseases Research Center, NOVA Medical School, Universidade Nova de Lisboa, Campo Mártires da Pátria 130, 1169-056, Lisboa, Portugal. ^[2] CEDOC - Chronic Diseases Research Center, NOVA Medical School, Universidade Nova de Lisboa, Campo Mártires da Pátria 130, 1169-056, Lisboa, Portugal; ProRegeM PhD Program, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Campo Mártires da Pátria 130, 1169-056, Lisboa, Portugal. ^[3] CEDOC - Chronic Diseases Research Center, NOVA Medical School, Universidade Nova de Lisboa, Campo Mártires da Pátria 130, 1169-056, Lisboa, Portugal; NOVA Medical School, Universidade Nova de Lisboa, Campo Mártires da Pátria 130, 1169-056, Lisboa, Portugal. Electronic address: gabriela.silva@nms.unl.pt. ^[4]

关键词 Diabetic retinopathy Ins2(Akita) mouse model Pigment epithelium-derived factor Placental growth factor Retina Retinal pigment epithelium