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Polo-like kinase 1 as a therapeutic target for malignant peripheral nerve sheath tumors (MPNST) and schwannomas.

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第一作者： Jianman,Guo

第一单位： Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania Philadelphia, PA 19104, USA.;Department of Clinical Pharmacy, Qilu Hospital of Shandong University Jinan 250012, Shandong, P. R. China.

作者： Jianman,Guo ^[1] ; Katherine E,Chaney ^[2] ; Kwangmin,Choi ^[2] ; Gabriela,Witek ^[3] ; Ami V,Patel ^[2] ; Hong,Xie ^[3] ; Danny,Lin ^[3] ; Kanupriya,Whig ^[4] ; Yao,Xiong ^[3] ; David C,Schultz ^[4] ; Nancy,Ratner ^[2] ; Jeffrey,Field ^[3]

作者单位： Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania Philadelphia, PA 19104, USA.;Department of Clinical Pharmacy, Qilu Hospital of Shandong University Jinan 250012, Shandong, P. R. China. ^[1] Division of Experimental Hematology and Cancer Biology Cincinnati Children's Hospital Medical Center Cincinnati, OH 45229, USA. ^[2] Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania Philadelphia, PA 19104, USA. ^[3] High Throughput Screening Core, Perelman School of Medicine, University of Pennsylvania Philadelphia, PA 19104, USA. ^[4]

关键词 HTS heat map high throughput screen siRNA screen signal transduction synthetic lethal von Recklinghausen disease xenograft

PMID 32266095

发布时间 2024-04-25

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