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Potent Anticancer Effect of the Natural Steroidal Saponin Gracillin Is Produced by Inhibiting Glycolysis and Oxidative Phosphorylation-Mediated Bioenergetics.

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第一作者： Hye-Young,Min

第一单位： Creative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul 08826, Korea.;Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Pharmacy, Seoul National University, Seoul 08826, Korea.;College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea.

作者： Hye-Young,Min ^[1] ; Honglan,Pei ^[2] ; Seung Yeob,Hyun ^[2] ; Hye-Jin,Boo ^[3] ; Hyun-Ji,Jang ^[2] ; Jaebeom,Cho ^[2] ; Ji Hye,Kim ^[4] ; Jaekyoung,Son ^[4] ; Ho-Young,Lee ^[1]

作者单位： Creative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul 08826, Korea.;Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Pharmacy, Seoul National University, Seoul 08826, Korea.;College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea. ^[1] Creative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul 08826, Korea. ^[2] Creative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul 08826, Korea.;College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea. ^[3] Department of Biomedical Sciences, Asan Medical Center, AMIST, University of Ulsan College of Medicine, Seoul 05505, Korea. ^[4]

关键词 breast cancer glycolysis gracillin lung cancer oxidative phosphorylation phosphoglycerate kinase 1

DOI 10.3390/cancers12040913

PMID 32276500

发布时间 2020-09-28

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