BREED based de novo hybridization approach: generating novel T790M/C797S-EGFR tyrosine kinase inhibitors to overcome the problem of mutation and resistance in non small cell lung cancer (NSCLC).

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作者： Harun M,Patel ^[1] ; Matin,Shaikh ^[1] ; Iqrar,Ahmad ^[1] ; Deepak,Lokwani ^[1] ; Sanjay J,Surana ^[1]

作者单位： Division of Bioinformatics, Department of Pharmaceutical Chemistry, R.C. Patel Institute of Pharmaceutical Education and Research, Maharashtra, India. ^[1]

关键词 ADME T790M/C797S-EGFR tyrosine kinase breed simulation

主题词苯胺化合物(Aniline Compounds);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);抗药性, 肿瘤(Drug Resistance, Neoplasm);人类(Humans);肺肿瘤(Lung Neoplasms);突变(Mutation);蛋白激酶抑制剂(Protein Kinase Inhibitors)

DOI 10.1080/07391102.2020.1754918

PMID 32276580

发布时间 2021-07-02

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Journal of biomolecular structure & dynamics

2021年39卷8期

2838-2856页

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BREED based de novo hybridization approach: generating novel T790M/C797S-EGFR tyrosine kinase inhibitors to overcome the problem of mutation and resistance in non small cell lung cancer (NSCLC).

Journal of biomolecular structure & dynamics

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Journal of biomolecular structure & dynamics

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BREED based de novo hybridization approach: generating novel T790M/C797S-EGFR tyrosine kinase inhibitors to overcome the problem of mutation and resistance in non small cell lung cancer (NSCLC).

Journal of biomolecular structure & dynamics

相似文献

Journal of biomolecular structure & dynamics

相关期刊

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