换一批
换一批NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients.
作者：
Sunny,Malhotra [1]
;
Carme,Costa [1]
;
Herena,Eixarch [1]
;
Christian W,Keller [2]
;
Lukas,Amman [3]
;
Helios,Martínez-Banaclocha [4]
;
Luciana,Midaglia [5]
;
Eduard,Sarró [6]
;
Isabel,Machín-Díaz [1]
;
Luisa M,Villar [7]
;
Juan Carlos,Triviño [8]
;
Begoña,Oliver-Martos [9]
;
Laura Navarro,Parladé [10]
;
Laura,Calvo-Barreiro [11]
;
Fuencisla,Matesanz [1]
;
Koen,Vandenbroeck [1]
;
Elena,Urcelay [12]
;
María-Luisa,Martínez-Ginés [13]
;
Amalia,Tejeda-Velarde [14]
;
Nicolás,Fissolo [15]
;
Joaquín,Castilló [16]
;
Alex,Sanchez [9]
;
Avril A B,Robertson [1]
;
Diego,Clemente [1]
;
Marco,Prinz [17]
;
Pablo,Pelegrin [18]
;
Jan D,Lünemann [19]
;
Carmen,Espejo [8]
;
Xavier,Montalban [4]
;
Manuel,Comabella [20]
作者单位：
Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
[1]
Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany.
[2]
Institute of Experimental Immunology, Laboratory of Neuroinflammation, University of Zurich, Zurich, Switzerland.
[3]
Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.
[4]
Faculty of Biology, University of Freiburg, Freiburg, Germany.
[5]
Biomedical Research Institute of Murcia (IMIB-Arrixaca), University Clinical Hospital Virgen de la Arrixaca, Murcia, Spain.
[6]
Renal Physiopathology Group, Institut de Recerca Vall d'Hebron (VHIR) - CIBBIM Nanomedicine, Barcelona, Spain.
[7]
Grupo de Neuroinmuno-Reparación, Hospital Nacional de Parapléjicos-SESCAM, Toledo, Spain.
[8]
Departments of Immunology and Neurology, Multiple Sclerosis Unit, Hospital Ramon y Cajal, (IRYCIS), Madrid, Spain.
[9]
Genomic Systems, Valencia, Spain.
[10]
Neuroimmunology and Neuroinflammation Group, Instituto de Investigación Biomédica de Málaga-IBIMA, UGC Neurociencias, Hospital Regional Universitario de Málaga, Málaga, Spain.
[11]
Department of Cell Biology and Immunology, Instituto de Parasitología y Biomedicina "López Neyra", Consejo Superior de Investigaciones Científicas (IPBLN-CSIC), Granada, Spain.
[12]
Universidad del País Vasco (UPV/EHU), Leioa, Spain.
[13]
IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.
[14]
Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
[15]
Department of Neurology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
[16]
Department of Genetics, Microbiology and Statistics, Universitat de Barcelona, Barcelona, Spain.
[17]
Statistics and Bioinformatics Unit, Vall d'Hebron Institut de Recerca, Barcelona, Spain.
[18]
School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australia.
[19]
Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.
[20]
Center for NeuroModulation (NeuroModul), Faculty of Medicine, University of Freiburg, Freiburg, Germany.
[21]
Center for Multiple Sclerosis, St, Michael's Hospital, University of Toronto, Toronto, ON, Canada.
[22]
主题词
成年人(Adult);动物(Animals);脑脊髓炎, 自身免疫性, 实验性(Encephalomyelitis, Autoimmune, Experimental);女(雌)性(Female);人类(Humans);炎性体(Inflammasomes);白细胞介素1β(Interleukin-1beta);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);多发性硬化, 慢性进行性(Multiple Sclerosis, Chronic Progressive);预后(Prognosis)
DOI
10.1093/brain/awaa084
PMID
32282893
发布时间
2022-01-05
- 浏览22
Brain
Brain
1414-1430页
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