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PRMT5-dependent transcriptional repression of c-Myc target genes promotes gastric cancer progression.

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第一作者： Ming,Liu

第一单位： The State Key Laboratory of Pharmaceutical Biotechnology, Department of Hematology, the Affiliated Drum Tower Hospital of Nanjing University Medical School, China-Australia Institute of Translational Medicine, School of Life Sciences, Nanjing University, Nanjing, China.

作者： Ming,Liu ^[1] ; Bing,Yao ^[2] ; Tao,Gui ^[1] ; Chan,Guo ^[1] ; Xiaobin,Wu ^[3] ; Jiahuang,Li ^[1] ; Lingling,Ma ^[1] ; Yexuan,Deng ^[1] ; Peipei,Xu ^[1] ; Ying,Wang ^[1] ; Dongjun,Yang ^[1] ; Qixiang,Li ^[1] ; Xiangwei,Zeng ^[1] ; Xinyu,Li ^[1] ; Ruifeng,Hu ^[1] ; Jingru,Ge ^[1] ; Zenong,Yu ^[1] ; Yugen,Chen ^[3] ; Bing,Chen ^[1] ; Junyi,Ju ^[1] ; Quan,Zhao ^[1]

作者单位： The State Key Laboratory of Pharmaceutical Biotechnology, Department of Hematology, the Affiliated Drum Tower Hospital of Nanjing University Medical School, China-Australia Institute of Translational Medicine, School of Life Sciences, Nanjing University, Nanjing, China. ^[1] The State Key Laboratory of Pharmaceutical Biotechnology, Department of Hematology, the Affiliated Drum Tower Hospital of Nanjing University Medical School, China-Australia Institute of Translational Medicine, School of Life Sciences, Nanjing University, Nanjing, China.;Department of Medical Genetics, Nanjing Medical University, Nanjing, China. ^[2] The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. ^[3]

关键词 PRMT5 c-Myc gastric cancer histone arginine methylation tumorigenesis