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Discovery of Membrane-Bound Pyrophosphatase Inhibitors Derived from an Isoxazole Fragment.

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第一作者： Niklas G,Johansson

第一单位： Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, P.O. Box 56 (Viikinkaari 5 E), FI-00014 Helsinki, Finland.

作者： Niklas G,Johansson ^[1] ; Ainoleena,Turku ^[1] ; Keni,Vidilaseris ^[2] ; Loïc,Dreano ^[1] ; Ayman,Khattab ^[3] ; Daniel,Ayuso Pérez ^[1] ; Aaron,Wilkinson ^[4] ; Yuezhou,Zhang ^[1] ; Matti,Tamminen ^[1] ; Evgeni,Grazhdankin ^[1] ; Alexandros,Kiriazis ^[1] ; Colin W G,Fishwick ^[4] ; Seppo,Meri ^[3] ; Jari,Yli-Kauhaluoma ^[1] ; Adrian,Goldman ^[5] ; Gustav,Boije Af Gennäs ^[1] ; Henri,Xhaard ^[1]

作者单位： Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, P.O. Box 56 (Viikinkaari 5 E), FI-00014 Helsinki, Finland. ^[1] Department of Biosciences, Division of Biochemistry, University of Helsinki, P.O. Box 56 (Viikinkaari 9), FI-00014 Helsinki, Finland. ^[2] Malaria Research Laboratory, Translational Immunology Research Program, Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, P.O. Box 21 (Haartmaninkatu 3), FI-00014 Helsinki, Finland. ^[3] School of Chemistry, University of Leeds, Woodhouse Lane, Leeds LS2 9JT, United Kingdom. ^[4] Department of Biosciences, Division of Biochemistry, University of Helsinki, P.O. Box 56 (Viikinkaari 9), FI-00014 Helsinki, Finland.;School of Biomedical Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Clarendon Way, Leeds LS2 9JT, United Kingdom. ^[5]

DOI 10.1021/acsmedchemlett.9b00537

PMID 32292570

发布时间 2020-09-28

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